Can a vitamin B3 pill help people with rare muscle disease?
NCT ID NCT05590468
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether nicotinamide riboside, a form of vitamin B3, can improve walking distance and muscle function in adults with mitochondrial myopathy, a rare muscle disorder. Thirty-four participants receive either the supplement or a placebo for several months. The main goal is to see if the supplement helps them walk farther in six minutes.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- nicotinamide riboside (a form of vitamin B3)
- What this could lead to
- If it works, this could point toward a simple vitamin supplement to help manage mitochondrial myopathy symptoms.
- What could go wrong
- This is a small, early-phase trial with only 34 people. The supplement may not improve walking or muscle function, and results may not apply to everyone with the condition.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.