Vitamin B3 pill may shield CLL patients from skin cancer

This study tests whether taking nicotinamide (a form of vitamin B3) twice daily for one year can reduce the number of new non-melanoma skin cancers in people with chronic lymphocytic leukemia (CLL) who have already had at least one such skin cancer. About 86 participants will be randomly assigned to receive either nicotinamide or a placebo. After one year, everyone will take nicotinamide for another year. The goal is to see if this simple supplement can lower skin cancer risk in this vulnerable group.