New drug combo shows promise for aggressive bladder cancer

NCT ID NCT06960577

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 20 times

Summary

This study tests whether adding the immunotherapy drug durvalumab to standard chemotherapy before bladder removal surgery is safe and effective for people with muscle-invasive bladder cancer. About 150 participants will receive the drug combination, then undergo surgery. The goal is to improve outcomes while managing side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Research Site

    RECRUITING

    Chermside, 4032, Australia

  • Research Site

    RECRUITING

    Elizabeth Vale, 5112, Australia

  • Research Site

    RECRUITING

    Heidelberg, 3084, Australia

  • Research Site

    RECRUITING

    Hong Kong, Australia

  • Research Site

    RECRUITING

    Kogarah, 2217, Australia

  • Research Site

    RECRUITING

    Macquarie University, 2109, Australia

  • Research Site

    RECRUITING

    Murdoch, 6150, Australia

  • Research Site

    RECRUITING

    Port Macquarie, 2444, Australia

  • Research Site

    RECRUITING

    St Leonards, 2065, Australia

  • Research Site

    RECRUITING

    Barretos, 14784-400, Brazil

  • Research Site

    WITHDRAWN

    Jaú, 17210-080, Brazil

  • Research Site

    WITHDRAWN

    Natal, 59075-740, Brazil

  • Research Site

    RECRUITING

    Porto Alegre, 91350-200, Brazil

  • Research Site

    WITHDRAWN

    Rio de Janeiro, 20230-130, Brazil

  • Research Site

    RECRUITING

    Santo André, 09060-650, Brazil

  • Research Site

    WITHDRAWN

    São José do Rio Preto, 15090-000, Brazil

  • Research Site

    RECRUITING

    São Paulo, 01246-000, Brazil

  • Research Site

    RECRUITING

    Hamilton, Ontario, L8V 5C2, Canada

  • Research Site

    NOT_YET_RECRUITING

    London, Ontario, N6A 5W9, Canada

  • Research Site

    WITHDRAWN

    Ottawa, Ontario, K1H 8L6, Canada

  • Research Site

    NOT_YET_RECRUITING

    Montreal, Quebec, H3T 1E2, Canada

  • Research Site

    RECRUITING

    Québec, Quebec, G1J 1Z4, Canada

  • Research Site

    RECRUITING

    Sherbrooke, Quebec, J1H 5N4, Canada

  • Research Site

    NOT_YET_RECRUITING

    Angers, 49055, France

  • Research Site

    WITHDRAWN

    Angers, 49933, France

  • Research Site

    NOT_YET_RECRUITING

    Bordeaux, 33075, France

  • Research Site

    NOT_YET_RECRUITING

    Chambray-lès-Tours, 37170, France

  • Research Site

    NOT_YET_RECRUITING

    Dijon, 21079, France

  • Research Site

    NOT_YET_RECRUITING

    Lille, 59037, France

  • Research Site

    NOT_YET_RECRUITING

    Lyon, 69008, France

  • Research Site

    NOT_YET_RECRUITING

    Marseille, 13009, France

  • Research Site

    NOT_YET_RECRUITING

    Montpellier, 34070, France

  • Research Site

    NOT_YET_RECRUITING

    Nice, 06189, France

  • Research Site

    NOT_YET_RECRUITING

    Nîmes, 30029, France

  • Research Site

    NOT_YET_RECRUITING

    Paris, 75010, France

  • Research Site

    NOT_YET_RECRUITING

    Paris, 75900, France

  • Research Site

    NOT_YET_RECRUITING

    Pierre-Bénite, 69310, France

  • Research Site

    NOT_YET_RECRUITING

    Poitiers, 86021, France

  • Research Site

    NOT_YET_RECRUITING

    Quint-Fonsegrives, 31130, France

  • Research Site

    NOT_YET_RECRUITING

    Rennes, 35000, France

  • Research Site

    NOT_YET_RECRUITING

    Rouen, 76230, France

  • Research Site

    NOT_YET_RECRUITING

    Strasbourg, 67033, France

  • Research Site

    NOT_YET_RECRUITING

    Suresnes, 92150, France

  • Research Site

    NOT_YET_RECRUITING

    Florence, 50139, Italy

  • Research Site

    NOT_YET_RECRUITING

    Orbassano, 10043, Italy

  • Research Site

    NOT_YET_RECRUITING

    Roma, 00144, Italy

  • Research Site

    NOT_YET_RECRUITING

    Amsterdam, 1066CX, Netherlands

  • Research Site

    NOT_YET_RECRUITING

    Nijmegen, 6500 HB, Netherlands

  • Research Site

    NOT_YET_RECRUITING

    Rotterdam, 3015 GD, Netherlands

  • Research Site

    NOT_YET_RECRUITING

    Barcelona, 08025, Spain

  • Research Site

    NOT_YET_RECRUITING

    Barcelona, 08035, Spain

  • Research Site

    NOT_YET_RECRUITING

    Barcelona, 08036, Spain

  • Research Site

    NOT_YET_RECRUITING

    Barcelona, 8003, Spain

  • Research Site

    NOT_YET_RECRUITING

    Girona, 17007, Spain

  • Research Site

    NOT_YET_RECRUITING

    Las Palmas de Gran Canaria, 35016, Spain

  • Research Site

    NOT_YET_RECRUITING

    Lugo, 27003, Spain

  • Research Site

    NOT_YET_RECRUITING

    Madrid, 28033, Spain

  • Research Site

    NOT_YET_RECRUITING

    Madrid, 28040, Spain

  • Research Site

    NOT_YET_RECRUITING

    Santiago de Compostela, 15706, Spain

Conditions

Explore the condition pages connected to this study.