New scan and genetic tests aim to catch cancer early in NF1 patients

NCT ID NCT02211768

First seen Jun 25, 2026 · Last updated Aug 05, 2026 · Updated 10 times

Summary

This study looked at people with neurofibromatosis type 1 (NF1) to better understand how harmless tumors (plexiform neurofibromas) turn into a rare cancer called MPNST. Ten participants had MRI, PET scans, and tumor biopsies. Researchers tested whether a special PET scan (FLT PET) could spot cancer better than standard scans, and they analyzed tumor genetics. The goal was to improve early detection, not to test a treatment.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

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