New study aims to predict cancer in NF1 patients before it starts

NCT ID NCT05677594

First seen Jan 12, 2026 · Last updated May 01, 2026 · Updated 15 times

Summary

This study follows 80 people with Neurofibromatosis type 1 (NF1) who are at high risk for developing malignant peripheral nerve sheath tumors (MPNST). Researchers will use yearly whole-body MRI scans and blood tests to track changes in nerve tumors over time. The goal is to find imaging and genetic markers that can predict which patients are most likely to develop cancer, so they can be caught early.

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Contacts and locations

Locations

  • Johns Hopkins University

    Baltimore, Maryland, 21287, United States

Conditions

Explore the condition pages connected to this study.