Can a common heartburn drug keep Kids' esophagitis at bay?

NCT ID NCT05267613

First seen Oct 31, 2025 · Last updated May 08, 2026 · Updated 29 times

Summary

This study looks at whether two different doses of Nexium can keep erosive esophagitis (a condition where the esophagus is damaged by stomach acid) from coming back in children aged 1 to 11. About 53 kids who have already healed from the condition will take Nexium for 16 weeks. Doctors will check if the esophagus stays healed using a camera test (endoscopy). The goal is to find a safe and effective dose for long-term control.

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Contacts and locations

Locations

  • Research Site

    Mobile, Alabama, 36604, United States

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    Sacramento, California, 95817, United States

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    Miami, Florida, 33122, United States

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    Miami, Florida, 33155, United States

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    Orlando, Florida, 32806, United States

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    Carmel, Indiana, 46290, United States

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    Shreveport, Louisiana, 71103, United States

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    The Bronx, New York, 10468, United States

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    Akron, Ohio, 44308, United States

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    Cleveland, Ohio, 44195, United States

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    Milwaukee, Wisconsin, 53226, United States

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    Córdoba, 5000, Argentina

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    Córdoba, X5016KEH, Argentina

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    Paraná, 3100, Argentina

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    Rosario, S2000DEJ, Argentina

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    Clayton, 3168, Australia

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    Namur, 5101, Belgium

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    Athens, 11527, Greece

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    Thessaloniki, 54642, Greece

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    Thessaloniki, 56249, Greece

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    Messina, 98125, Italy

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    Naples, 80131, Italy

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    Naples, 80138, Italy

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    Roma, 00137, Italy

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    Roma, 00161, Italy

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    Vilnius, LT-08406, Lithuania

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    Braga, 4710, Portugal

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    Coimbra, 3000-602, Portugal

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    Lisbon, 1169-045, Portugal

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    Lisbon, 1500-650, Portugal

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    Lisbon, 1998-018, Portugal

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    Porto, 4099-001, Portugal

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    Porto, 4200-319, Portugal

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    Viana do Castelo, 4901-858, Portugal

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    Badalona, 08916, Spain

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    Santiago de Compostela, 15706, Spain

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    Seville, 41009, Spain

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    Seville, 41013, Spain

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    Hanoi, 100000, Vietnam

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    Hanoi, 10000, Vietnam

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    Hà Nội, 100000, Vietnam

  • Research Site

    Hochiminh, 700000, Vietnam

Conditions

Explore the condition pages connected to this study.