Scientists test Next-Generation shots in fight against TB

NCT ID NCT05547464

Summary

This study is testing two new investigational vaccines designed to protect against tuberculosis (TB). Researchers are evaluating the safety and immune response of different dose levels in healthy adults who have previously received the standard BCG vaccine. The goal is to find a safe and effective dose that could potentially offer better protection against TB infection.

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Contacts and locations

Locations

  • Africa Health Research Institute (AHRI)

    Mtubatuba, 3935, South Africa

  • CAPRISA eThekweni Clinical Research Site

    Berea, 4001, South Africa

  • Centre for Lung Infection and Immunity UCT Lung Institute

    Cape Town, 7700, South Africa

  • Centro de Investigação e Treino em Saúde da Polana Caniço (CISPOC) (recruiting participants for Part B only)

    Maputo, 1102, Mozambique

  • Centro de Investigação em Saúde de Manhiça (CISM) (recruiting participants for Part B only)

    Manhiça, 1929, Mozambique

  • Desmond Tutu Health Foundation - Masiphumele Research Office

    Cape Town, 7975, South Africa

  • South African Tuberculosis Vaccine Initiative SATVI

    Cape Town, 6850, South Africa

  • The Aurum Institute Tembisa CRC Clinic 4

    Tembisa, 1632, South Africa

Conditions

Explore the condition pages connected to this study.