Breakthrough trial aims to replace toxic treatment for deadly fungal infection

NCT ID NCT06525389

Summary

This large Phase 3 trial aims to find safer and more effective treatments for talaromycosis, a serious fungal infection that is a leading cause of death in people with advanced HIV in Southeast Asia. It will test if a single strong dose of a newer, less toxic drug works better than the current two-week toxic treatment, and if adding a second drug improves outcomes. The study also explores a new strategy for deciding when to stop preventive medication after recovery.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Bach Mai Hospital

    Hanoi, Vietnam

    Contact Email: •••••@•••••

  • Duke University Medical Center

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital for Tropical Diseases

    Ho Chi Minh City, 7000, Vietnam

    Contact

  • National Hospital for Tropical Diseases

    Hanoi, Vietnam

    Contact

  • Pham Ngoc Thach University of Medicine

    Ho Chi Minh City, 7000, Vietnam

    Contact

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.