Scientists train donor cells to hunt down blood cancer

NCT ID NCT02494167

Summary

This early-stage study is testing a new therapy for people with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) that has returned or persists after standard treatment, including a stem cell transplant. Researchers take immune cells (T cells) from the patient's original stem cell donor and train them in a lab to recognize and attack four specific proteins found on the cancer cells. The main goal is to find the safest dose of these specially trained cells, which are given as an infusion after the transplant.

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Contacts and locations

Locations

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Texas Children's Hospital

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.