New hope for PNH patients when standard treatments fail

NCT ID NCT07154745

Summary

This study is testing a combination of two new drugs, pozelimab and cemdisiran, for people with PNH whose current standard treatment isn't fully controlling the disease. The goal is to see if this new combination can better reduce the destruction of red blood cells and improve symptoms like fatigue. The study will enroll about 35 adults who are already on a C5 inhibitor but still have high levels of a blood marker (LDH) showing their disease is active.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AOU Careggi

    RECRUITING

    Florence, Tuscany, 50134, Italy

  • Ewha Womans University Mokdong Hospital

    RECRUITING

    Seoul, 07985, South Korea

  • Hospital San Pedro de Alcantara

    RECRUITING

    Cáceres, 10003, Spain

  • In-Vivo Sp. z o.o.

    RECRUITING

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-048, Poland

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

Conditions

Explore the condition pages connected to this study.