New hope for PNH patients: trial tests Next-Gen drug for stubborn anemia

NCT ID NCT07187401

Summary

This study is testing an experimental drug called ALN-CFB in people with Paroxysmal Nocturnal Hemoglobinuria (PNH) who still have anemia despite being on standard C5 inhibitor therapy. The main goals are to check the drug's safety, how the body processes it, and see if it can help improve anemia by targeting a different part of the immune system. It's a small, early-stage study where some participants will receive the drug and others will receive a placebo.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Samsung Medical Center

    RECRUITING

    Seoul, 6351, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Seoul National University Hospital

    RECRUITING

    Seoul, 03080, South Korea

  • Severance Hospital

    RECRUITING

    Seoul, 3722, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. James's University Hospital

    RECRUITING

    Leeds, West Yorkshire, LS97TF, United Kingdom

    Contact Email: •••••@•••••

  • St. Vincent Hospital - The Catholic University of Korea

    RECRUITING

    Suwon, Gyeonggi-do, 16247, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Catholic University of Korea, Seoul St. Mary's Hospital

    RECRUITING

    Seoul, 06591, South Korea

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Toronto General Hospital

    RECRUITING

    Toronto, Ontario, M5G 2C4, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.