New imaging agent for lymphoma shows promise but trial stalls

NCT ID NCT06125028

Terminated Diagnosis Sponsor: Pentixapharm AG Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tested a new radioactive imaging agent called [68Ga]Ga-PentixaFor to see if it could better detect lymphoma tumors compared to the standard PET scan. The study aimed to enroll adults with marginal zone lymphoma who had not yet been treated. However, the trial was terminated early after only 8 participants, so the results are not conclusive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: [68Ga]Ga-PentixaFor (a radioactive imaging agent)
What this could lead to: If successful, this imaging agent could provide a more accurate way to stage certain lymphomas, potentially guiding better treatment decisions.
What could go wrong: The trial was terminated early with only 8 participants, so results are very limited. It is unclear if the agent works better than the current standard.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Lymphoma, B-Cell, Marginal Zone marginal zone lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MARGINAL ZONE LYMPHOMA

Contacts and locations

Locations

CHU La Timone

Marseille, 13005, France
CHU de Bordeaux

Bordeaux, 33600, France
CHU de Nantes

Nantes, 44093, France
Clinica Universidad de Navarra

Pamplona, Navarre, 31008, Spain
Fondazione Policlinico Universitario Agostino Gemelli IRCCS

Rome, 00168, Italy
Hôpital Cochin

Paris, 75014, France
IRCCS Azienda Ospedaliero-Universitaria di Bologna

Bologna, 40138, Italy
L'IRCCS Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST S.r.l

Meldola, 47014, Italy
Medizinische Universität Innsbruck

Innsbruck, 6020, Austria
Ospedale San Raffaele S.r.l.

Milan, 20132, Italy
Universitätsklinikum Essen

Essen, 45147, Germany
Universitätsklinikum Würzburg

Würzburg, 97080, Germany

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