Promising new combo therapy targets rare brain cancer
NCT ID NCT04446962
First seen Oct 31, 2025 · Last updated May 12, 2026 · Updated 19 times
Summary
This study tests adding either lenalidomide or ibrutinib to standard chemotherapy for adults aged 18-65 with newly diagnosed primary central nervous system lymphoma (a rare brain cancer). The goal is to improve treatment response before a stem cell transplant. The trial first finds the safest dose, then compares how well each drug combo works.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CH Colmar
Colmar, France
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CH côte Basque
Bayonne, 64100, France
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CHRU Lille
Lille, 69000, France
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CHU Amiens
Amiens, France
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CHU Angers
Angers, France
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CHU Besançon
Besançon, France
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CHU Caen
Caen, France
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CHU Clermont-Ferrand
Clermont-Ferrand, France
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CHU Créteil
Créteil, France
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CHU Dijon
Dijon, France
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CHU Grenoble
Grenoble, France
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CHU La Timone Marseille
Marseille, France
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CHU Limoges
Limoges, France
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CHU Lyon
Lyon, France
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CHU Nancy
Nancy, France
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CHU Nantes
Nantes, France
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CHU Nîmes - Carémeau
Nîmes, 30029, France
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CHU Pitié-Salpêtrière
Paris, 75013, France
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CHU Poitiers
Poitiers, France
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CHU Rennes
Rennes, 35000, France
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CHU Strasbourg-Hôpital Hautepierre
Strasbourg, 67098, France
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CHU Tours
Tours, France
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Centre Henri Becquerel
Rouen, 76000, France
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Centre Lacassagne
Nice, France
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Hôpital Cochin
Paris, 75006, France
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IUCT -Oncopole
Toulouse, France
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Institut Bergonié
Bordeaux, France
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Institut Curie
Paris, 75005, France
Conditions
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