Major trial tests powerful new combo for blood cancer

NCT ID NCT02252172

Completed Disease control Sponsor: Janssen Research & Development, LLC Source: ClinicalTrials.gov ↗

Summary

This large, completed Phase 3 study tested whether adding a targeted drug (daratumumab) to a standard two-drug therapy (lenalidomide and dexamethasone) was better at controlling newly diagnosed multiple myeloma. It involved 737 older adults or those ineligible for intensive stem cell transplant. The goal was to see if the three-drug combination could keep the cancer from progressing longer than the standard two-drug treatment.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

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Birmingham, Alabama, United States
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Mobile, Alabama, United States
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Glendale, Arizona, United States
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Berkeley, California, United States
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Beverly Hills, California, United States
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El Cajon, California, United States
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Greenbrae, California, United States
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Los Angeles, California, United States
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Oceanside, California, United States
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San Diego, California, United States
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West Hills, California, United States
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Whittier, California, United States
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Denver, Colorado, United States
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Fort Collins, Colorado, United States
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Glenwood Springs, Colorado, United States
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New Haven, Connecticut, United States
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Norwalk, Connecticut, United States
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Washington D.C., District of Columbia, United States
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Boca Raton, Florida, United States
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Boynton Beach, Florida, United States
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Fort Lauderdale, Florida, United States
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Fort Myers, Florida, United States
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Hollywood, Florida, United States
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Jacksonville, Florida, United States
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Lake City, Florida, United States
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St. Petersburg, Florida, United States
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Weston, Florida, United States
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Atlanta, Georgia, United States
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Augusta, Georgia, United States
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Macon, Georgia, United States
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Marietta, Georgia, United States
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Chicago, Illinois, United States
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Niles, Illinois, United States
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Fort Wayne, Indiana, United States
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Iowa City, Iowa, United States
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Louisville, Kentucky, United States
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Lafayette, Louisiana, United States
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Marrero, Louisiana, United States
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Shreveport, Louisiana, United States
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Annapolis, Maryland, United States
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Baltimore, Maryland, United States
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Frederick, Maryland, United States
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Boston, Massachusetts, United States
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Detroit, Michigan, United States
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Duluth, Minnesota, United States
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Rochester, Minnesota, United States
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Kansas City, Missouri, United States
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St Louis, Missouri, United States
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Omaha, Nebraska, United States
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Hooksett, New Hampshire, United States
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Brick, New Jersey, United States
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Hackensack, New Jersey, United States
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Livingston, New Jersey, United States
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Plainfield, New Jersey, United States
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Summit, New Jersey, United States
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Mineola, New York, United States
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New York, New York, United States
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Rochester, New York, United States
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Asheboro, North Carolina, United States
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Charlotte, North Carolina, United States
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Pinehurst, North Carolina, United States
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Winston-Salem, North Carolina, United States
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Canton, Ohio, United States
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Cleveland, Ohio, United States
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Columbus, Ohio, United States
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Bend, Oregon, United States
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Bethlehem, Pennsylvania, United States
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Pittsburgh, Pennsylvania, United States
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Spartanburg, South Carolina, United States
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Sioux Falls, South Dakota, United States
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Chattanooga, Tennessee, United States
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Nashville, Tennessee, United States
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Arlington, Texas, United States
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Edinburg, Texas, United States
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Fort Sam Houston, Texas, United States
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Fort Worth, Texas, United States
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Houston, Texas, United States
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Plano, Texas, United States
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San Antonio, Texas, United States
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Ogden, Utah, United States
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Seattle, Washington, United States
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Spokane, Washington, United States
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Tacoma, Washington, United States
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Box Hill, Australia
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Fitzroy, Australia
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Footscray, Australia
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Kogarah, Australia
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Kurralta Park, Australia
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Nedlands, Australia
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New South Wales, Australia
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Woodville, Australia
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Woolloongabba, Australia
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Innsbruck, Austria
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Linz, Austria
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Salzburg, Austria
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Vienna, Austria
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Wien Wien, Austria
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Bruges, Belgium
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Brussels, Belgium
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Haine Saint Paul La Louviere, Belgium
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Leuven, Belgium
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Liège, Belgium
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Calgary, Alberta, Canada
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Nova Scotia, Nova Scotia, Canada
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Toronto, Ontario, Canada
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Greenfield Park, Quebec, Canada
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Montreal, Quebec, Canada
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Québec, Quebec, Canada
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N/a N/a, Canada
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Aarhus C, Denmark
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Odense, Denmark
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Vejle, Denmark
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Amiens N/a Picardie, France
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Angers, France
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Bayonne, France
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Bretagne, France
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Caen, France
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Cergy-Pontoise, France
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Chalon-sur-Saône, France
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Clermont-Ferrand, France
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Créteil, France
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Dijon, France
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Dunkirk, France
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Grenoble, France
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La Roche-sur-Yon, France
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Le Chesnay, France
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Le Mans, France
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Lille, France
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Limoges, France
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Lyon, France
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Marseille, France
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Metz-Tessy, France
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Montivilliers, France
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Montpellier, France
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Mulhouse, France
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Nantes, France
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Nice, France
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Paris, France
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Perpignan, France
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Pessac, France
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Périgueux, France
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Poitiers, France
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Reims, France
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Rennes, France
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Rouen, France
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Saint-Brieuc, France
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Saint-Priest-en-Jarez, France
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Saint-Quentin, France
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St-Malo, France
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Strasbourg, France
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Toulouse, France
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Tours, France
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Vandœuvre-lès-Nancy, France
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Aschaffenburg, Germany
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Bad Berka, Germany
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Bonn, Germany
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Braunschweig, Germany
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Dresden, Germany
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Essen, Germany
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Frankfurt, Germany
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Hanover, Germany
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Heidelberg, Germany
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Hessen, Germany
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Kiel, Germany
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Koblenz, Germany
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Mainz, Germany
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Mannheim, Germany
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Rostock, Germany
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Schwerin, Germany
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Stuttgart, Germany
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Tübingen, Germany
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Ulm, Germany
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Villingen-Schwenningen, Germany
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Dublin, Ireland
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Galway, Ireland
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Hadera, Israel
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Haifa, Israel
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Jerusalem, Israel
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Nahariya, Israel
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Petah Tikva, Israel
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Tel Aviv, Israel
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Hilversum, Netherlands
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Hoofddorp, Netherlands
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Rotterdam, Netherlands
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Tilburg, Netherlands
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Falun, Sweden
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Gothenburg, Sweden
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Halmstad, Sweden
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Helsingborg, Sweden
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Huddinge, Sweden
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Luleå, Sweden
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Lund, Sweden
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Örebro, Sweden
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Stockholm, Sweden
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Aberdeen, United Kingdom
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Canterbury, United Kingdom
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Dundee, United Kingdom
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Leeds, United Kingdom
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London, United Kingdom
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Manchester, United Kingdom
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Nottingham, United Kingdom
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Oxford, United Kingdom
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Plymouth, United Kingdom
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Southampton, United Kingdom
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Truro, United Kingdom
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Wolverhampton, United Kingdom

Conditions

Explore the condition pages connected to this study.

MULTIPLE MYELOMA