Global race for better mesothelioma treatment: new drug combo enters final testing phase

NCT ID NCT06097728

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This large global study is testing whether adding an experimental drug called volrustomig to standard chemotherapy works better than current standard treatments for advanced pleural mesothelioma, a serious cancer often linked to asbestos exposure. About 825 adults with mesothelioma that cannot be removed by surgery will receive either the new combination or one of two standard treatment options. The main goal is to see if the new combination helps people live longer compared to existing treatments.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

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Locations

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WITHDRAWN

Phoenix, Arizona, 85054, United States
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Duarte, California, 91010, United States
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Santa Rosa, California, 95403, United States
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Aurora, Colorado, 80045, United States
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Jacksonville, Florida, 32224, United States
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Atlanta, Georgia, 30322, United States
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Chicago, Illinois, 60637, United States
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Baltimore, Maryland, 21231, United States
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Rochester, Minnesota, 55905, United States
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St Louis, Missouri, 63110, United States
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East Brunswick, New Jersey, 08816, United States
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Commack, New York, 11725, United States
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Valhalla, New York, 10595, United States
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Cleveland, Ohio, 44111, United States
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Cleveland, Ohio, 44124, United States
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Cleveland, Ohio, 44195, United States
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Columbus, Ohio, 43210, United States
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Independence, Ohio, 44131, United States
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Portland, Oregon, 97213, United States
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Portland, Oregon, 97225, United States
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Portland, Oregon, 97239, United States
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Philadelphia, Pennsylvania, 19104, United States
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Houston, Texas, 77030, United States
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Fairfax, Virginia, 22031, United States
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ACTIVE_NOT_RECRUITING

Chermside, 4032, Australia
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Clayton, 3168, Australia
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Melbourne, 3000, Australia
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Nedlands, 6009, Australia
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Westmead, 2145, Australia
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Anderlecht, 1070, Belgium
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Antwerp, 2020, Belgium
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COMPLETED

Ghent, 9000, Belgium
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Hasselt, 3500, Belgium
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Leuven, 3000, Belgium
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Sint-Niklaas, 9100, Belgium
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Barretos, 14784-400, Brazil
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Fortaleza, 60336-045, Brazil
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João Pessoa, 58013-140, Brazil
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Porto Alegre, 91350-200, Brazil
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Rio de Janeiro, 22281-100, Brazil
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Santo André, 09060-650, Brazil
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São Paulo, 01246-000, Brazil
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Edmonton, Alberta, T6G 1Z2, Canada
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Hamilton, Ontario, L8V 1C3, Canada
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London, Ontario, N6A 5W9, Canada
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Ottawa, Ontario, K1H 8L6, Canada
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Toronto, Ontario, M5G 1X6, Canada
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Montreal, Quebec, H2X 0C1, Canada
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Québec, Quebec, G1V 4G5, Canada
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Beijing, 100142, China
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Beijing, 100210, China
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Changchun, 130021, China
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Changsha, 410013, China
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Chengdu, 610042, China
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Chongqing, 400030, China
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Guangzhou, 510100, China
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Hangzhou, 310022, China
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Harbin, 150049, China
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Kunming, 650118, China
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Lanzhou, 730000, China
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Nanchang, 330006, China
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Ningbo, 315100, China
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Qingdao, 266003, China
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Shandong, China
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Shanghai, 200032, China
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Shenyang, 110044, China
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Taiyuan, 030000, China
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Taiyuan, 030032, China
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Tianjin, 300050, China
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Tianjin, 300060, China
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Wuhan, 430030, China
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Xi'an, 710061, China
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Zhengzhou, 450008, China
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Zhengzhou, 450052, China
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ACTIVE_NOT_RECRUITING

Aarhus N, 8200, Denmark
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Copenhagen, 2100, Denmark
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COMPLETED

Brest, 29200, France
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Créteil, 94010, France
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Le Mans, 72037, France
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Lille, 59037, France
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Lyon, 69373, France
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Marseille, 13015, France
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Montpellier, 34298, France
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Paris, 75877, France
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COMPLETED

Rouen, 76031, France
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Saint-Herblain, 44800, France
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Strasbourg, 67091, France
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Toulouse, 31059, France
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Berlin, 13125, Germany
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Berlin, 14109, Germany
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Bochum, 44791, Germany
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Cologne, 51109, Germany
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Essen, 45122, Germany
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Essen, 45130, Germany
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Gauting, 82131, Germany
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Georgsmarienhütte, 49124, Germany
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Großhansdorf, 22927, Germany
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Hamburg, 21075, Germany
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Heidelberg, 69126, Germany
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Kiel, 24105, Germany
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Münster, 48153, Germany
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Regensburg, 93049, Germany
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ACTIVE_NOT_RECRUITING

Alessandria, 15100, Italy
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Bari, 70124, Italy
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Bergamo, 24125, Italy
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Milan, 20141, Italy
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Monza, 20052, Italy
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Orbassano, 10043, Italy
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Padua, 35128, Italy
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Parma, 43100, Italy
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Rozzano, 20089, Italy
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Varese, 21100, Italy
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Amagasaki-shi, 660-8550, Japan
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Hakodate-shi, 040-8611, Japan
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Hiroshima, 734-8551, Japan
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Kitaadachi-gun, 362-0806, Japan
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Kitakyushu-shi, 807-8555, Japan
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Matsuyama, 791-0280, Japan
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Nagoya, 466-8560, Japan
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Nishinomiya-shi, 663-8501, Japan
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Okayama, 702-8055, Japan
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Osakasayama-shi, 589-8511, Japan
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Tokyo, 104-0045, Japan
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Ube-shi, 755-0241, Japan
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ACTIVE_NOT_RECRUITING

Amsterdam, 1066CX, Netherlands
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Eindhoven, 5623EJ, Netherlands
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Rotterdam, 3015 GD, Netherlands
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COMPLETED

Lørenskog, 1478, Norway
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Oslo, 450, Norway
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WITHDRAWN

Bydgoszcz, 85-796, Poland
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Bystra, 43-360, Poland
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Olsztyn, 10-357, Poland
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Poznan, 60-569, Poland
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Rzeszów, 35-241, Poland
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Warsaw, 02-781, Poland
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Cape Town, 7570, South Africa
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eManzimtoti, 4126, South Africa
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SUSPENDED

Johannesburg, 2013, South Africa
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Johannesburg, 2193, South Africa
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Kimberly, 8301, South Africa
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Polokwane, 0700, South Africa
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Pretoria, 0002, South Africa
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Pretoria, 0081, South Africa
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WITHDRAWN

Cheongju-si, 28644, South Korea
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ACTIVE_NOT_RECRUITING

Seoul, 03080, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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Ulsan, 44033, South Korea
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Barakaldo, 48903, Spain
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Barcelona, 8035, Spain
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Madrid, 28041, Spain
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Oviedo, 33011, Spain
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Baden, CH-5405, Switzerland
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Basel, 4031, Switzerland
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Bern, 3010, Switzerland
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Fribourg, 1700, Switzerland
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Sankt Gallen, 9007, Switzerland
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Kaohsiung City, 80756, Taiwan
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Taichung, 40705, Taiwan
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Tainan, 70403, Taiwan
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Taipei, 10002, Taiwan
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Taoyuan District, 333, Taiwan
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WITHDRAWN

Adana, 01060, Turkey (Türkiye)
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SUSPENDED

Ankara, 06280, Turkey (Türkiye)
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Ankara, 06800, Turkey (Türkiye)
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Diyarbakır, 21280, Turkey (Türkiye)
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Izmir, 35110, Turkey (Türkiye)
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Cambridge, CB20QQ, United Kingdom
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Cardiff, Wales, CF5 6NF, United Kingdom
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Leeds, LS9 7TF, United Kingdom
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Leicester, LE1 5WW, United Kingdom
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London, NW1 2PG, United Kingdom
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London, SE1 9RT, United Kingdom
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London, SW3 6JJ, United Kingdom
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Manchester, M23 9LT, United Kingdom
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Newcastle upon Tyne, NE2 4HH, United Kingdom
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Portsmouth, PO6 3LY, United Kingdom
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Taunton, TA1 5DA, United Kingdom

Conditions

Explore the condition pages connected to this study.

UNRESECTABLE PLEURAL MESOTHELIOMA