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New hope for stubborn lung infections that resist standard treatments

NCT ID NCT04630145

Completed Disease control Sponsor: Janssen Pharmaceutical K.K. Source: ClinicalTrials.gov ↗

Summary

This study tested whether adding a drug called bedaquiline to standard antibiotics works better for adults with hard-to-treat MAC lung infections. Researchers compared bedaquiline against another standard drug in 129 participants over 24 weeks. The main goal was to see if the new combination could clear the infection from participants' lungs more effectively.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Asan Medical Center

    Seoul, 05505, South Korea

  • Chonnam National University Hospital

    Gwangju, 61469, South Korea

  • Fukui Prefectural Hospital

    Fukui-shi, 910-0846, Japan

  • Fukujuji Hospital

    Kiyose, 204-0022, Japan

  • Fukuoka University Chikushi Hospital

    Chikushino-shi, 818-8502, Japan

  • Gifu Prefectural General Medical Center

    Gifu, 500-8717, Japan

  • Hamamatsu Rosai Hospital

    Hamamatsu, 430-8525, Japan

  • Hokkaido Medical Center

    Sapporo Nishi-Ku, 063-0005, Japan

  • JRC Wakayama Medical Center

    Wakayama, 640 8558, Japan

  • Kanagawa Cardiovascular And Respiratory Center

    Yokohama, 236-0051, Japan

  • Kaohsiung Medical University Chung Ho Memorial Hospital

    Kaohsiung City, 80756, Taiwan

  • Keio University Hospital

    Shinjuku-ku, 160-8582, Japan

  • Kinki-chuo Chest Medical Center

    Sakai, 591-8555, Japan

  • Kobe City Medical Center West Hospital

    Kobe Nagata-Ku, 653-0013, Japan

  • Kojunkai Daido Clinic

    Nagoya, 457-8511, Japan

  • Matsunami General Hospital

    Hashima-gun, 501-6062, Japan

  • Matsunami Health Promotion Clinic

    Hashimagun Kasamatsucho, 501-6062, Japan

  • Matsusaka Municipal Hospital

    Matsusaka, 515-8544, Japan

  • Musashino Red Cross Hospital

    Musashino, 180-8610, Japan

  • Nagano Prefectural Shinshu Medical Center

    Suzaka, 386-8610, Japan

  • Nagaoka Red Cross Hospital

    Nagaoka, 940-2085, Japan

  • Nagasaki University Hospital

    Nagasaki, 852-8501, Japan

  • National Center for Global Health and Medicine

    Shinjuku, 162-8655, Japan

  • National Hospital Organization Ehime Medical Center

    Tōon, 791-0281, Japan

  • National Hospital Organization Fukuoka Higashi Medical Center

    Koga, 811-3195, Japan

  • National Hospital Organization Himeji Medical Center

    Himeji, 670-8520, Japan

  • National Hospital Organization Ibarakihigashi

    Funaishikawa, 319-1113, Japan

  • National Hospital Organization Kochi National Hospital

    Kochi, 780-8077, Japan

  • National Hospital Organization Kyoto Medical Center

    Kyoto, 612-8555, Japan

  • National Hospital Organization Minami Kyoto Hospital

    Jōyō, 610-0113, Japan

  • National Hospital Organization Nagoya Medical Center

    Nagoya, 460-0001, Japan

  • National Hospital Organization Nara Medical Center

    Shichijō, 630-8053, Japan

  • National Hospital Organization Nishiniigata Chuo Hospital

    Niigata, 950-2085, Japan

  • National Hospital Organization Omuta Hospital

    Omuta, 837-0911, Japan

  • National Hospital Organization Osaka Toneyama Medical Center

    Toyonaka-shi, 560-8552, Japan

  • National Hospital Organization Sagamihara National Hospital

    Sagamihara, 252-0392, Japan

  • National Hospital Organization Tenryu Hospital

    Hamamatue, 434-8511, Japan

  • National Hospital Organization Tokyo Medical Center

    Tokyo, 152-8902, Japan

  • National Hospital Organization Tokyo National Hospital

    Tokyo, 204-8585, Japan

  • National Taiwan University Hospital

    Taipei, 10002, Taiwan

  • Rakuwakai Otowa Hospital

    Kyoto, 607-8062, Japan

  • Saitama City Hospital

    Saitama-shi, 336-8522, Japan

  • Saitama Medical University Hospital

    Iruma-gun, 350-0495, Japan

  • Saitama Prefectural Cardiovascular and Respiratory Center

    Kumagaya, 360-0197, Japan

  • Samsung Medical Center

    Seoul, 135-230, South Korea

  • Seirei Hamamatsu General Hospital

    Hamamatsu, 430-8558, Japan

  • Shimonoseki City Hospital

    Yamaguchi, 750-0041, Japan

  • St. Luke's International Hospital

    Chūōku, 104 8560, Japan

  • Taichung Veterans General Hospital

    Taichung, 40705, Taiwan

  • Taipei Veterans General Hospital

    Taipei, 112, Taiwan

  • The Catholic University of Korea, Incheon St. Mary's Hospital

    Incheon, 403-720, South Korea

  • Tohoku Medical And Pharmaceutical University Hospital

    Sendai, 983-8512, Japan

  • Tokyo Shinagawa Hospital

    Shinagawa-ku, 140-8522, Japan

  • Toyota Kosei Hospital

    Toyota, 470-0396, Japan

  • Toyota Memorial Hospital

    Toyota-shi, 471-8513, Japan

Conditions

Explore the condition pages connected to this study.

TREATMENT-REFRACTORY MYCOBACTERIUM AVIUM COMPLEX-LUNG DISEASE (MAC-LD)