New hope for lymphoma patients Who've run out of options

NCT ID NCT04442022

Recruiting now Disease control Sponsor: Karyopharm Therapeutics Inc Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding a new drug called selinexor to standard chemotherapy works better for people with aggressive lymphoma that has returned or stopped responding to previous treatments. The trial will involve about 500 patients who cannot receive stem cell transplants or CAR-T therapy. Researchers will compare the new combination against standard treatment to see if it helps control the cancer longer with acceptable side effects.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AOU City of Health and Science of Turin
COMPLETED

Turin, Torino, 10126, Italy
AOU Maggiore della Carità SCDU Ematologia
RECRUITING

Novara, Novara, 28100, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
AOU Ospedali Riuniti-Università Politecnica delle Marche Clinica di Ematologia
RECRUITING

Ancona, Ancona, 60020, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
AOU Policlinico S.Orsola Malpighi di Bologna, University of Bologna
WITHDRAWN

Bologna, Bologna, 40138, Italy
Arizona Oncology Associates
RECRUITING

Tucson, Arizona, 85711, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Assuta Ashdod Medical Center
RECRUITING

Ashdod, 7747629, Israel

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Assuta medical centers - Ramat Hachayal
COMPLETED

Tel Aviv, 6423906, Israel
Azienda Ospedaliera Ospedali Riuniti Villa Sofia Cervello
RECRUITING

Palermo, Sicily, 90146, Italy

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Contact
CM Pratia Poznań
COMPLETED

Skorzewo, Wielkopolska, 60819, Poland
Comprehensive Cancer Centers of Nevada - Town Center
WITHDRAWN

Las Vegas, Nevada, 89169, United States
DIP. Oncologia- Ematologia, UOSD Centro Diagnosie TerapiaDei Linfomi
COMPLETED

Pescara, Pescara, 65124, Italy
Department of Lymphoid Malignancies, Maria Sklodowska-Curie National Research Institute of Oncology
COMPLETED

Warsaw, 02-781, Poland
Fondatione Policlinico Universitario A. Gemelli
RECRUITING

Rome, Rome, 00168, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Gabrail Cancer Center Research LLC
WITHDRAWN

Canton, Ohio, 44718, United States
Hadassah Medical Center
WITHDRAWN

Jerusalem, 9103401, Israel
Hospital Hietzing
WITHDRAWN

Vienna, Austria, 1130, Austria
Hospital Universitario La Paz
COMPLETED

Madrid, Madrid, 28046, Spain
Hospital Vall Hebron
COMPLETED

Barcelona, Barcelona, 08035, Spain
Hospital Virgen del Rocío
COMPLETED

Seville, Seville, 41013, Spain
Huaxi Hospital Sichuan University
COMPLETED

Chengdu, Sichuan, 610044, China
Institut Catala D'oncolocia
RECRUITING

Barcelona, Barcelona, 09809, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Institut català d'oncologia-hospital germans trias i pujol
RECRUITING

Badalona, Barcelona, 08916, Spain

Contact Phone: •••-•••-•••• Email: •••••@•••••

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Institute of Hematology and Transfusion Medicine
COMPLETED

Warsaw, 00-791, Poland
Investigative Clinical Research of Indiana, LLC
WITHDRAWN

Indianapolis, Indiana, 46260, United States
Ironwood Physicians P.C. dba Ironwood Cancer and Research Centers
COMPLETED

Chandler, Arizona, 85224, United States
Jiangsu Province Hospital
COMPLETED

Nanjing, Jiangsu, 210029, China
Kepler Universitaetskrankenhaus Med Campu III - Onkologie
WITHDRAWN

Linz, Austria, 4021, Austria
Klinika Hematologii, Nowotworów Krwi i Transplantacji Szpiku Uniwersytecki Szpital Kliniczny im. Jana Mikulicza - Radeckiego we Wrocławiu
COMPLETED

Wroclaw, Radeckiego, 50-367, Poland
National Cancer Institute
RECRUITING

Naples, Napoli, 1-80131, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
New Mexico Cancer Care Alliance
WITHDRAWN

Albuquerque, New Mexico, 87106, United States
Norton Cancer Institute, St. Matthews
RECRUITING

Louisville, Kentucky, 40207, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Pratia MCM Krakow
RECRUITING

Krakow, Lesser, 30-510, Poland

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Pratia Onkologia Katowice
COMPLETED

Katowice, Silesian Voivodeship, 40-523, Poland
Providence Regional Cancer Partnership
WITHDRAWN

Everett, Washington, 98201, United States
Rabin Medical Center
COMPLETED

Petah Tikva, 4941492, Israel
Rambam health care campus (Department of Hematology & Bone Marrow Transplantation)
WITHDRAWN

Haifa, 3109601, Israel
Ruijin Hospital Affiliated to The Shanghai Jiao Tong University Medical School
COMPLETED

Huangpu, Shanghai Municipality, 200025, China
Soroka Medical Center
COMPLETED

Beersheba, 8457108, Israel
Sourasky Medical Center
WITHDRAWN

Tel Aviv, 6423906, Israel
Stony Brook
RECRUITING

Stony Brook, New York, 11794, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Szpitale pomorskie gdynia dept of haematology
RECRUITING

Gdynia, Pomeranian Voivodeship, 81-519, Poland

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
Texas Oncology - Fort Worth
WITHDRAWN

Fort Worth, Texas, 76104, United States
Texas Oncology - Medical City Dallas
WITHDRAWN

Dallas, Texas, 75230, United States
Texas Oncology - Plano East
WITHDRAWN

Plano, Texas, 75075, United States
Texas Oncology - Presbyterian Dallas Cancer Center
WITHDRAWN

Dallas, Texas, 75231, United States
Texas Oncology - Sammons
WITHDRAWN

Dallas, Texas, 75246, United States
Texas Oncology - Tyler
RECRUITING

Tyler, Texas, 75702, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
The First Affiliated Hospital of Soochow University
COMPLETED

Suzhou, Jiangsu, 215006, China
The Oncology Institute (TOI) Clinical Research
RECRUITING

Cerritos, California, 90703, United States

Contact Email: •••••@•••••

Contact
The University of Texas Health Science Center at Tyler DBA UT Health East Texas HOPE Cancer Center
COMPLETED

Tyler, Texas, 75702, United States
The first affiliated Hospital, Zhejiang University
COMPLETED

Hangzhou, Zhejiang, 310003, China
Tulane Cancer Center
WITHDRAWN

New Orleans, Louisiana, 70112, United States
UOC Ematologia ad Indirizzo Oncologico, AORN "Sant'Anna e San Sebastiano"
RECRUITING

Caserta, Caserta, 81100, Italy

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
University of Maryland Greenebaum Comprehensive Cancer Center
RECRUITING

Baltimore, Maryland, 21201, United States

Contact Phone: •••-•••-•••• Email: •••••@•••••

Contact
University of Vienna, Medical Clinic I, Hematology
WITHDRAWN

Vienna, Austria, 1090, Austria
Wolfson Medical Center
WITHDRAWN

Holon, 5822012, Israel
Zhongshan Hospital Fudan University
COMPLETED

Xuhui, Shanghai Municipality, 200032, China

Conditions

Explore the condition pages connected to this study.

RELAPSED/REFRACTORY DIFFUSE LARGE B CELL LYMPHOMA