New cancer drug combo aims to outperform standard treatment in major trial

NCT ID NCT06149286

Recruiting now Disease control Sponsor: Regeneron Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a new drug combination works better than the current standard treatment for two types of lymphoma that have returned or stopped responding to prior therapy. It will involve about 470 adults with relapsed or hard-to-treat follicular lymphoma or marginal zone lymphoma. The trial directly compares the new combination of odronextamab and lenalidomide against the established treatment of rituximab and lenalidomide.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

A Beneficencia Portuguesa de Sao Paulo, Oncology House
RECRUITING

São Paulo, 01321000, Brazil
A.O.U. Citta della Salute e della Scienza di Torino
RECRUITING

Turin, Piedmont, 10126, Italy
A.O.U. di Modena
RECRUITING

Modena, 41124, Italy
AOU Maggiore della Carita
RECRUITING

Novara, 28100, Italy
ASST Grande Ospedale Metropolitano Niguarda - Main Address
RECRUITING

Milan, 20162, Italy
Aidport
RECRUITING

Skorzewo, Wielkopolska, 60185, Poland
Algemeen Ziekenhuis AZ Delta
RECRUITING

Roeselare, West-Vlaanderen, 8800, Belgium
Amaral Carvalho Hospital
RECRUITING

Jaú, São Paulo, 17210-080, Brazil
Ankara University Faculty of Medicine
RECRUITING

Mamak, Ankara, 06620, Turkey (Türkiye)
Asan Medical Center
RECRUITING

Seoul, 05505, South Korea
Assistance Publique-Hopitaux de Paris (AP-HP)
RECRUITING

Paris, 75571, France
Assuta Ashdod Medical Center
RECRUITING

Ashdod, 7747629, Israel
Assuta Medical Centers
RECRUITING

Tel Aviv, 6971028, Israel
Avicenne Hospital
RECRUITING

Bobigny, Île-de-France Region, 93000, France
Azienda Ospedaliera Spedali Civili di Brescia
RECRUITING

Brescia, 25123, Italy
Azienda Ospedaliera di Perugia
RECRUITING

Perugia, 06132, Italy
Barking, Havering and Redbridge University Hospitals NHS Trust
RECRUITING

Romford, RM7 0AG, United Kingdom
Boca Raton Clinical Research (BRCR) Global
RECRUITING

Plantation, Florida, 33322, United States
CHU de Rennes
RECRUITING

Rennes, Brittany Region, 35033, France
Calvary Mater Newcastle
RECRUITING

Waratah, New South Wales, 2298, Australia
Candiolo Cancer Institute, FPO, IRCCS
RECRUITING

Candiolo, Torino, 10060, Italy
Centre Francois Magendie
RECRUITING

Pessac, Gironde, 33600, France
Centre Henri Becquerel
RECRUITING

Rouen, Normandy, 76038, France
Centre Hospitalier Metropole Savoie
RECRUITING

Chambéry, Savoie, 73000, France
Centre Hospitalier Regional Universitaire de Tours
RECRUITING

Tours, Centre-Val de Loire, 37044, France
Centre Hospitalier Universitaire (CHU) Montpellier
RECRUITING

Montpellier, 34290, France
Centre Hospitalier Universitaire at Universite Catholique de Louvain Namur
RECRUITING

Yvoir, Namur, 5530, Belgium
Centre Hospitalier d'Avignon
RECRUITING

Avignon, 84000, France
Centro Di Riferimento Oncologico (CRO), Aviano, National Cancer Institute
RECRUITING

Aviano, Pordenone, 33081, Italy
Centro Gaucho Integrado
RECRUITING

Porto Alegre, Rio Grande do Sul, 90110-270, Brazil
Chaim Sheba Medical Center
RECRUITING

Ramat Gan, 5265601, Israel
Chang Gung Medical Foundation Chia Yi Branch
RECRUITING

Buzi, Chiayi County, 613, Taiwan
Chang Gung Memorial Hospital
RECRUITING

Taoyuan, 333, Taiwan
Chang Gung Memorial Hospital Kaohsiung
RECRUITING

Kaohsiung City, 83301, Taiwan
Changhua Christian Hospital
RECRUITING

Changhua, 500-06, Taiwan
Chiang Mai University
RECRUITING

Chiang Mai, 50200, Thailand
Chulalongkorn University
RECRUITING

Bangkok, Krung Thep Maha Nakhon [Bangko], 10330, Thailand
Clinic Frankfurt (Oder)
RECRUITING

Frankfurt am Main, Hesse, 15236, Germany
Clinical Research Alliance Inc
WITHDRAWN

Westbury, New York, 11590, United States
Dartmouth Cancer Center
RECRUITING

Lebanon, New Hampshire, 03756, United States
David Geffen School of Medicine at UCLA
RECRUITING

Los Angeles, California, 90095, United States
Derriford Hospital and the Royal Eye Infirmary
RECRUITING

Plymouth, Devon, PL6 8DH, United Kingdom
Dokuz Eylul University
RECRUITING

Izmir, 35340, Turkey (Türkiye)
Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital
RECRUITING

Yenimahalle, Ankara, 06200, Turkey (Türkiye)
Ege University
RECRUITING

Izmir, 35100, Turkey (Türkiye)
Epworth Freemasons
RECRUITING

East Melbourne, Victoria, 3121, Australia
Fakultni Nemocnice Brno
RECRUITING

Brno, 62500, Czechia
Federico II University
RECRUITING

Naples, 80131, Italy
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
RECRUITING

Milan, 20122, Italy
Fondazione IRCCS Policlinico San Matteo
RECRUITING

Pavia, 27100, Italy
Fundacion Jimenez Diaz University Hospital
RECRUITING

Madrid, 28040, Spain
Gachon University Gil Medical Center
RECRUITING

Incheon, Namdong-Gu, 21565, South Korea
Galilee Medical Center
RECRUITING

Nahariya, 2210001, Israel
Gazi University
RECRUITING

Ankara, Central Anatolia, 06100, Turkey (Türkiye)
Gustave Roussy
RECRUITING

Villejuif, Île-de-France Region, 94800, France
Hadassah Medical Center
RECRUITING

Jerusalem, 91200, Israel
Hattiesburg Clinic
RECRUITING

Hattiesburg, Mississippi, 39401, United States
Hopital Saint Louis
RECRUITING

Paris, 75010, France
Hopital Saint Vincent-de-Paul
RECRUITING

Lille, Nord, 5900, France
Hopital Victor Dupouy Argenteuil
RECRUITING

Argenteuil, Île-de-France Region, 95100, France
Hospital Ampang
RECRUITING

Ampang, Selangor, 68000, Malaysia
Hospital Clinic de Barcelona
RECRUITING

Barcelona, 08036, Spain
Hospital Erasto Gaertner
RECRUITING

Curitiba, Paraná, 81520-060, Brazil
Hospital Queen Elizabeth
RECRUITING

Kota Kinabalu, Sabah, 88586, Malaysia
Hospital Sao Rafael
RECRUITING

Salvador, Estado de Bahia, 40285-000, Brazil
Hospital Sirio Libanes
RECRUITING

São Paulo, 01308-050, Brazil
Hospital Sirio Libanes Brasilia
RECRUITING

Brasília, Federal District, 70200-730, Brazil
Hospital Sultanah Aminah Jhor Bahru
RECRUITING

Johor Bahru, Johor, 80100, Malaysia
Hospital Universitario Central de Asturias
RECRUITING

Oviedo, Principality of Asturias, 33011, Spain
Hospital Universitario HM Sanchinarro
RECRUITING

Madrid, 28050, Spain
Hospital Universitario Marques de Valdecilla
RECRUITING

Santander, Cantabria, 39008, Spain
Hospital Universitario Quironsalud Madrid
RECRUITING

Pozuelo de Alarcón, Madrid, 28223, Spain
Hospital Universitario Ramon y Cajal
RECRUITING

Madrid, 28034, Spain
Hospital Universitario de Salamanca
RECRUITING

Salamanca, 37007, Spain
Hospital Universitario12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Virgen De Las Nieves De Granada
RECRUITING

Granada, 18014, Spain
Hospital de Clinicas de Porto Alegre
RECRUITING

Porto Alegre, Rio Grande do Sul, 90035-903, Brazil
Hospital de la Santa Creu i Sant Pau
RECRUITING

Barcelona, 08041, Spain
Indiana University and Comprehensive Cancer Center
RECRUITING

Indianapolis, Indiana, 46202, United States
Inje University Busan Paik Hospital
RECRUITING

Busan, 47392, South Korea
Institut Catala d'Oncologia
RECRUITING

L'Hospitalet de Llobregat, Barcelona, 08908, Spain
Institut Curie
RECRUITING

Saint-Cloud, 92210, France
Institut Jules Bordet
RECRUITING

Brussels, 1000, Belgium
Institut Paoli-Calmettes
RECRUITING

Marseille, Bouches Du Rhone, 13009, France
Instituto Nacional de Cancer Jose Alencar Gomes da Silva
RECRUITING

Rio de Janeiro, 20231050, Brazil
Instituto Valenciano de Oncologia
RECRUITING

Valencia, 46009, Spain
Istanbul University, Istanbul Medical Faculty
RECRUITING

Istanbul, 34093, Turkey (Türkiye)
Istituto Europeo di Oncologia
RECRUITING

Milan, 20141, Italy
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori
RECRUITING

Meldola, Forli-Cesena, 47014, Italy
James Paget University Hospitals NHS Foundation Trust
RECRUITING

Great Yarmouth, NR31 6LA, United Kingdom
Jeonbuk National University Hospital
RECRUITING

Jeonju, Jeollabuk, 54907, South Korea
Kaohsiung Medical University Hospital
RECRUITING

Kaohsiung City, 80756, Taiwan
Kepler University Hospital
RECRUITING

Linz, Upper Austria, 4020, Austria
Klinikum Wels-Grieskirchen
RECRUITING

Wels, 4600, Austria
LMU Klinikum
RECRUITING

Munich, Bavaria, 80337, Germany
Liverpool Hospital
RECRUITING

Liverpool, New South Wales, 2170, Australia
MVZ fuer Haematologie und Onkologie Rhein-Kreis GmbH
RECRUITING

Neuss, 41462, Germany
Medical University Vienna
RECRUITING

Vienna, 1090, Austria
Nantes University Hospital
RECRUITING

Nantes, Pays de la Loire Region, 44093, France
Narodowy Instytut Onkologii
RECRUITING

Warsaw, 02-781, Poland
National Cheng Kung University Hospital
RECRUITING

Tainan, 701, Taiwan
National Taiwan University Hospital
RECRUITING

Taipei, 10002, Taiwan
Ondokuz Mayıs University
RECRUITING

Samsun, 55270, Turkey (Türkiye)
Ordensklinikum Linz
RECRUITING

Linz, Osterreich, 4020, Austria
Ospedale Policlinico San Martino IRCCS
RECRUITING

Genoa, Genova, 16132, Italy
Ospedale Santa Maria delle Croci
RECRUITING

Ravenna, 48121, Italy
Pindara Private Hospital
RECRUITING

Benowa, Queensland, 4217, Australia
Polyclinique Bordeaux Nord Aquitaine
RECRUITING

Bordeaux, Gironde, 33077, France
Pratia MCM Krakow
RECRUITING

Krakow, Malopolska, 30-510, Poland
Pratia Onkologia Katowice
RECRUITING

Katowice, 40-519, Poland
Pratia Poznan Medical Center
COMPLETED

Poznan, Wielkopolska, 60185, Poland
Prohealth Care Inc
RECRUITING

Waukesha, Wisconsin, 53188, United States
Pusan National University Hospital
RECRUITING

Busan, 49241, South Korea
Rabin Medical Center
RECRUITING

Petah Tikva, 49100, Israel
Robert-Bosch-Krankenhaus
RECRUITING

Stuttgart, Baden-Wurttemberg, 70376, Germany
Royal Cornwall Hospitals NHS Trust
RECRUITING

Truro, Cornwall, TR1 3LJ, United Kingdom
Royal Hobart Hospital
RECRUITING

Hobart, Tasmania, 7000, Australia
S Gerardo Hospital
RECRUITING

Monza, Monza E Brianza, 20900, Italy
Sakarya University Medical Faculty
RECRUITING

Sakarya, 54290, Turkey (Türkiye)
Salisbury Foundation Trust
RECRUITING

Salisbury, Hampshire, SP6 2ND, United Kingdom
Samsung Medical Center
RECRUITING

Seoul, 06351, South Korea
Santa Maria della Misericordia
RECRUITING

Udine, 33100, Italy
Seoul National University Hospital
RECRUITING

Seoul, 3080, South Korea
Seoul St Marys Hospital
RECRUITING

Seoul, 137-701, South Korea
Show Chwan Memorial Hospital
RECRUITING

Changhua, 50008, Taiwan
Son Espases University Hospital
RECRUITING

Palma, Balearic Islands, 07120, Spain
South Warwickshire NHS Foundation Trust
RECRUITING

Warwick, CV34 5BW, United Kingdom
Specjalistyczny Szpital im A. Sokolowskiego w Walbrzychu
RECRUITING

Wałbrzych, Lower Silesian Voivodeship, 58-309, Poland
Sriraj Hospital
RECRUITING

Bangkok, 10700, Thailand
St. Vincents Hospital - The Catholic University of Korea
RECRUITING

Suwon, Gyeonggi-do, 16247, South Korea
Stadtisches Krankenhaus Kiel
RECRUITING

Kiel, 24116, Germany
Stauferklinikum
RECRUITING

Mutlangen, Baden-Wurttemberg, 73557, Germany
Stony Brook University Hospital
RECRUITING

Stony Brook, New York, 11794, United States
Subang Jaya Medical Center
RECRUITING

Subang Jaya, Selangor, 47500, Malaysia
Szpital Uniwersytecki Nr2 Bydgoszcz
WITHDRAWN

Bydgoszcz, 85-168, Poland
TUM Fakultat fur Medizin - Klinikum Rechts der Isar
RECRUITING

Munich, Bavaria, 81675, Germany
Taipei Medical University - Shuang Ho Hospital
RECRUITING

New Taipei City, 23561, Taiwan
Taipei Municipal Wan Fang Hospital
RECRUITING

Taipei, 116, Taiwan
Taipei Veterans General Hospital
RECRUITING

Taipei, 11217, Taiwan
Tekirdag Namik Kemal University Hospital
RECRUITING

Tekirdağ, Suleymanpasa, 59100, Turkey (Türkiye)
The Hillingdon Hospital
RECRUITING

Uxbridge, Middlesex, UB8 3NN, United Kingdom
The Royal Marsden NHS Foundation Trust
RECRUITING

Sutton, Surrey, SM2 5PT, United Kingdom
The Tel Aviv Sourasky Medical Center
RECRUITING

Tel Aviv, 64239, Israel
Tri-Service General Hospital
RECRUITING

Taipei, 11490, Taiwan
Ulsan University Hospital
RECRUITING

Ulsan, 44033, South Korea
Universitair Ziekenhuis (UZ) Gent/ Ghent University Hospital
RECRUITING

Ghent, Oost-Vlaanderen, 9000, Belgium
Universitatsmedizin der Johannes-Gutenberg Universitat Mainz
RECRUITING

Mainz, Rhineland-Palatinate, 55131, Germany
University Hospital Doctor Peset
RECRUITING

Valencia, 46017, Spain
University Hospital Halle Saale
RECRUITING

Halle, 6120, Germany
University Hospital Hradec Kralove
RECRUITING

Hradec Králové, East Bohemia, 50005, Czechia
University Hospital Kralovske Vinohrady
RECRUITING

Prague, 10034, Czechia
University Hospital Vall d'Hebron
RECRUITING

Barcelona, 08035, Spain
University Hospital Virgen del Rocio
RECRUITING

Seville, 41013, Spain
University Hospital of Santiago de Compostela
RECRUITING

Santiago de Compostela, A Coruna, 15706, Spain
University Hospitals Dorset
RECRUITING

Bournemouth, Dorset, BH7 7DW, United Kingdom
University of Bologna Dipartimento di Medicina Specialistica Diagnostica e Sperimentale
RECRUITING

Bologna, 40138, Italy
University of Malaya Medical Centre
RECRUITING

Kuala Lumpur, Negeri / Wilayah Persekutuan, 50603, Malaysia
Uniwersytecki Szpital Kliniczny
RECRUITING

Wroclaw, Lower Silesian Voivodeship, 50-367, Poland
Uniwersytecki Szpital Kliniczny Nr 4 w Lublinie, Centrum Innowacyjnych Terapii
RECRUITING

Lublin, Lublin Voivodeship, 20-090, Poland
Uniwersyteckie Centrum Kliniczne
RECRUITING

Gdansk, Pomeranian Voivodeship, 80-952, Poland
Uopeccan Hospital do Cancer de Cascavel
RECRUITING

Cascavel, Paraná, 85806-300, Brazil
VM Medical Park Mersin Hospital
RECRUITING

Mezitli, Mersin, 33200, Turkey (Türkiye)
Vseobecna Fakultni Nemocnice V Praze
RECRUITING

Prague, 12808, Czechia
Wojewodzkie Wielospecjalistyczne Centrum Onkologii i Traumatologii im. Mikolaja Kopernika w Lodzi (Copernicus Memorial Hospital)
RECRUITING

Lodz, 93-513, Poland
Yeouido St. Marys Hospital
RECRUITING

Seoul, 07345, South Korea
Yeyungnam University Medical Center
WITHDRAWN

Daegu, 42415, South Korea
Yonsei University Health System
RECRUITING

Seoul, 03722, South Korea
Ziekenhuis Netwerk Antwerpen Stuivenberg
RECRUITING

Antwerp, 2060, Belgium
Zonguldak Bulent Ecevit University
RECRUITING

Zonguldak, 67600, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.

MARGINAL ZONE LYMPHOMA (MZL) RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA RELAPSED/REFRACTORY MARGINAL ZONE LYMPHOMA (R/R MZL)