Early trial tests promising new combo for Tough-to-Treat lymphoma

NCT ID NCT05685173

Summary

This is an early-stage study testing the safety and side effects of a new two-drug combination (REGN5837 plus odronextamab) for people with aggressive B-cell non-Hodgkin lymphoma that has come back or stopped responding to at least two prior treatments. The main goal is to find a safe dose for future testing. Researchers will also check if the treatment helps shrink the cancer.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Amsterdam University Medical Centre, location AMC

    RECRUITING

    Amsterdam, 1100AZ, Netherlands

  • CHU de Bordeaux

    RECRUITING

    Talence, Nouvelle-Aquitaine, 33404, France

  • City of Hope

    RECRUITING

    Duarte, California, 91010, United States

  • Erasmus Medical Center Rotterdam

    RECRUITING

    Rotterdam, South Holland, 3015, Netherlands

  • Gustave Roussy

    RECRUITING

    Villejuif, Île-de-France Region, 94800, France

  • Harvard Medical School - Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

  • Hopital Saint Louis

    RECRUITING

    Paris, 75010, France

  • Hospital Vall d'Hebron

    RECRUITING

    Barcelona, 08035, Spain

  • Icahn School of Medicine at Mount Sinai

    RECRUITING

    New York, New York, 10029, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • NYU Langone Health Perlmutter Cancer Center

    RECRUITING

    New York, New York, 10016, United States

  • Norton Cancer Institute

    RECRUITING

    Louisville, Kentucky, 40207, United States

  • Royal Cornwall Hospitals NHS Trust

    RECRUITING

    Truro, Cornwall, TR1 3LJ, United Kingdom

  • Rutgers Cancer Institute of New Jersey

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

  • Southampton General Hospital

    RECRUITING

    Southampton, Hampshire, SO16 6YD, United Kingdom

  • The Christie NHS Foundation Trust

    RECRUITING

    Manchester, M20 4BX, United Kingdom

  • UT Southwestern

    RECRUITING

    Dallas, Texas, 75390, United States

  • University Hospital and Research Institute

    RECRUITING

    Madrid, 28041, Spain

  • University of California Los Angeles (UCLA) Medical Center

    RECRUITING

    Santa Monica, California, 90404, United States

  • Western General Hospital

    RECRUITING

    Edinburgh, Scotland, EH4 2XU, United Kingdom

Conditions

Explore the condition pages connected to this study.