Breakthrough trial aims to extend lives in aggressive lung cancer

NCT ID NCT07005128

Recruiting now Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding a new drug called tarlatamab to standard chemotherapy and immunotherapy helps people with advanced small-cell lung cancer live longer. Researchers will compare two treatment combinations in 330 participants who haven't received prior treatment for their cancer. The main goal is to see which approach provides better survival and disease control.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AZ Delta Campus Rumbeke
RECRUITING

Roeselare, 8800, Belgium
Alexandra Hospital
RECRUITING

Athens, 11528, Greece
Allina Health System dba Allina Health Cancer Institute
RECRUITING

Minneapolis, Minnesota, 55407, United States
Ankara Bilkent Sehir Hastanesi
RECRUITING

Ankara, 06800, Turkey (Türkiye)
Asklepios Fachkliniken Muenchen Gauting
RECRUITING

Gauting, 82130, Germany
Azienda Ospedaliera San Giovanni Addolorata
RECRUITING

Roma, 00184, Italy
Bagcilar Medipol Mega Universite Hastanesi
RECRUITING

Istanbul, 34214, Turkey (Türkiye)
Baptist Cancer Center
RECRUITING

Memphis, Tennessee, 38120, United States
Beijing Cancer Hospital
RECRUITING

Beijing, Beijing Municipality, 100080, China
Beijing Cancer Hospital
RECRUITING

Beijing, 100142, China
Cancer Care Specialists of Illinois
RECRUITING

Decatur, Illinois, 62526, United States
Cancer Center of Kansas, Heritage Plaza Medical Building
RECRUITING

Wichita, Kansas, 67214, United States
Cancer Partners of Nebraska
RECRUITING

Lincoln, Nebraska, 68516, United States
Cemic
RECRUITING

Ciudad Autonoma de Buenos Aires, Buenos Aires, C1431FWO, Argentina
Cenantron Centro Avançado de Tratamento Oncologico Ltda
RECRUITING

Belo Horizonte, Minas Gerais, 30130-090, Brazil
Centre Hospitalier Intercommunal de Creteil
RECRUITING

Créteil, 94010, France
Centre Hospitalier Universitaire Nord
RECRUITING

Marseille, 13915, France
Centre Hospitalier Universitaire de Nantes - Hopital Nord Laennec
RECRUITING

Saint-Herblain, 44800, France
Centre Hospitalier Universitaire de Toulouse - Hopital Larrey
RECRUITING

Toulouse, 31059, France
Centre Hospitalier Universitaire-Universite Catholique de Louvain Namur-Site Godinne
RECRUITING

Yvoir, 5530, Belgium
Centre Leon Berard
RECRUITING

Lyon, 69008, France
Centro Ricerche Cliniche Di Verona Societa responsabilita limitata
RECRUITING

Verona, 37126, Italy
Centro de Pesquisa do Hospital Albert Einstein
RECRUITING

São Paulo, São Paulo, 05652-900, Brazil
Centrum Pulmonologii i Torakochirurgii w Bystrej
RECRUITING

Bystra, 43-360, Poland
Chris OBrien Lifehouse
RECRUITING

Camperdown, New South Wales, 2050, Australia
Chungbuk National University Hospital
RECRUITING

Cheongju Chungbuk, 28644, South Korea
Colorado West Healthcare System dba Grand Valley Oncology
RECRUITING

Grand Junction, Colorado, 81505, United States
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Ege Universitesi Tip Fakultesi Hastanesi
RECRUITING

Izmir, 35100, Turkey (Türkiye)
Erasmus Medisch Centrum
RECRUITING

Rotterdam, 3015 GD, Netherlands
European Interbalkan Medical Center
RECRUITING

Thessaloniki, 57001, Greece
Fujian Cancer Hospital
RECRUITING

Fuzhou, 350011, China
Fund Faculdade Regional Med Sao Jose Rio Preto
RECRUITING

São José do Rio Preto, São Paulo, 15090-000, Brazil
Goztepe Prof Dr Suleyman Yalcin Sehir Hastanesi
RECRUITING

Istanbul, 34722, Turkey (Türkiye)
Harbin Medical University Cancer Hospital
RECRUITING

Harbin, Heilongjiang, 150000, China
Henan Cancer Hospital
RECRUITING

Zhengzhou, Henan, 450003, China
Henry Dunant Hospital Center
RECRUITING

Athens, 11526, Greece
Hopital d instruction des armees sainte anne
RECRUITING

Toulon, 83800, France
Hopitaux universitaires de Geneve
RECRUITING

Geneva, 1211, Switzerland
Hospital Clinic i Provincial de Barcelona
RECRUITING

Barcelona, Catalonia, 08036, Spain
Hospital Cuf Tejo
RECRUITING

Lisbon, 1350-352, Portugal
Hospital Regional Universitario de Malaga
RECRUITING

Málaga, Andalusia, 29010, Spain
Hospital Sao Lucas da Pontificia Universidade Catolica do Rio Grande do Sul
RECRUITING

Porto Alegre, Rio Grande do Sul, 90610-000, Brazil
Hospital Universitari Vall d Hebron
RECRUITING

Barcelona, Catalonia, 08035, Spain
Hospital Universitari i Politecnic La Fe
RECRUITING

Valencia, Valencia, 46026, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, 28041, Spain
Hospital Universitario Austral
RECRUITING

Pilar, Buenos Aires, B1629ODT, Argentina
Hospital Universitario Puerta de Hierro Majadahonda
RECRUITING

Majadahonda, Madrid, 28222, Spain
Hospital Universitario Ramon y Cajal
RECRUITING

Madrid, 28034, Spain
Hospital da Luz, SA
RECRUITING

Lisbon, 1500-650, Portugal
Hospital de la Santa Creu i Sant Pau
RECRUITING

Barcelona, Catalonia, 08041, Spain
Humanitas Gavazzeni
RECRUITING

Bergamo, 24125, Italy
Hyogo Cancer Center
RECRUITING

Akashi-shi, Hyōgo, 673-8558, Japan
IRCCS Istituto Oncologico Europeo
RECRUITING

Milan, 20141, Italy
IRCCS Istituto Tumori Giovanni Paolo II
RECRUITING

Bari, 70124, Italy
Iatriko Diavalkaniko Thessalonikis
RECRUITING

Thessaloniki, 57001, Greece
Indiana University Melvin and Bren Simon Cancer Center
RECRUITING

Indianapolis, Indiana, 46202, United States
Institut Curie
RECRUITING

Paris, 75005, France
Institutul Oncologic Prof Dr Ion Chiricuta Cluj-Napoca
RECRUITING

Cluj-Napoca, 400015, Romania
Instytut Gruzlicy i Chorob Pluc
RECRUITING

Warsaw, 01-138, Poland
Istituto Romagnolo per lo Studio dei Tumori Dino Amadori
RECRUITING

Meldola (FC), 47014, Italy
Jessa Ziekenhuis - Campus Virga Jesse
RECRUITING

Hasselt, 3500, Belgium
Jiamusi Cancer Hospital
RECRUITING

Jiamusi, Heilongjiang, 154007, China
Jiangxi Cancer hospital
RECRUITING

Nanchang, Jiangxi, 330029, China
Kaiser Permanente Medical Center
RECRUITING

Portland, Oregon, 97227, United States
Kansai Medical University Hospital
RECRUITING

Hirakata-shi, Osaka, 573-1191, Japan
Kantonsspital Graubuenden
RECRUITING

Chur, 7000, Switzerland
Kindai University Hospital
RECRUITING

Sakai-shi, Osaka, 590-0197, Japan
Klinikum Chemnitz GmbH
RECRUITING

Chemnitz, 09113, Germany
Krankenhaus Koeln-Merheim - Kliniken der Stadt Koeln gGmbH
RECRUITING

Cologne, 51109, Germany
Krankenhaus Nordwest
RECRUITING

Frankfurt am Main, 60488, Germany
Kurume University Hospital
RECRUITING

Kurume-shi, Fukuoka, 830-0011, Japan
Kyushu University Hospital
RECRUITING

Fukuoka, Fukuoka, 812-8582, Japan
Liga Norte-Riograndense Contra O Cancer
RECRUITING

Natal, Rio Grande do Norte, 59062-000, Brazil
LungenClinic Grosshansdorf GmbH
RECRUITING

Großhansdorf, 22927, Germany
Maastricht Universitair Medisch Centrum
RECRUITING

Maastricht, 6229 HX, Netherlands
Matrai Gyogyintezet
RECRUITING

Gyöngyös, 3200, Hungary
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Medizinische Universitaet Graz
RECRUITING

Graz, 8036, Austria
Meir Medical Center
RECRUITING

Kfar Saba, 4428164, Israel
Memorial Ankara Hastanesi
RECRUITING

Ankara, 06520, Turkey (Türkiye)
Monash Medical Centre
RECRUITING

Clayton, Victoria, 3168, Australia
National Cancer Center
RECRUITING

Goyang-si Gyeonggi-do, 10408, South Korea
National Cheng Kung University Hospital
RECRUITING

Tainan, 70403, Taiwan
National Hospital Organization Hokkaido Cancer Center
RECRUITING

Sapporo, Hokkaido, 003-0804, Japan
National Hospital Organization Shikoku Cancer Center
RECRUITING

Matsuyama, Ehime, 791-0280, Japan
Nebraska Cancer Specialists
RECRUITING

Omaha, Nebraska, 68130, United States
Niigata Cancer Center Hospital
RECRUITING

Niigata, Niigata, 951-8566, Japan
Okayama University Hospital
RECRUITING

Okayama, Okayama-ken, 700-8558, Japan
Oncology Hematology Care, Inc
RECRUITING

Cincinnati, Ohio, 45242, United States
Orlando Health Cancer Institute
RECRUITING

Kissimmee, Florida, 34744, United States
Osaka International Cancer Institute
RECRUITING

Osaka, Osaka, 541-8567, Japan
Presbyterian Intercommunity Hospital Health Whitter Hospital
RECRUITING

Whittier, California, 90602, United States
Prince of Wales Hospital, Chinese University of Hong Kong
RECRUITING

Shatin, New Territories, Hong Kong
Queen Mary Hospital, The University of Hong Kong
RECRUITING

Hong Kong, Hong Kong
Rabin Medical Center
RECRUITING

Petah Tikva, 4941492, Israel
Reformatus Pulmonologiai Centrum
RECRUITING

Törökbálint, 2045, Hungary
Regionshospitalet Godstrup
RECRUITING

Herning, 7400, Denmark
Rigshospitalet
RECRUITING

Copenhagen, 2100, Denmark
Saint Bernards Medical Center
RECRUITING

Jonesboro, Arkansas, 72401, United States
Saitama Medical University International Medical Center
RECRUITING

Hidaka-shi, Saitama, 350-1298, Japan
Sakarya Egitim ve Arastirma Hastanesi
RECRUITING

Sakarya, 54290, Turkey (Türkiye)
Sanatorio Parque SA
RECRUITING

Rosario, Santa Fe Province, 2000, Argentina
Severance Hospital Yonsei University Health System
RECRUITING

Seoul, 03722, South Korea
Shandong Cancer Hospital
RECRUITING

Jinan, Shandong, 250117, China
Shanghai Chest Hospital
RECRUITING

Shanghai, Shanghai Municipality, 200030, China
Shanghai Pulmonary Hospital
RECRUITING

Shanghai, Shanghai Municipality, 200433, China
Shanxi Provincial Cancer Hospital
RECRUITING

Taiyuan, Shanxi, 030009, China
Shizuoka Cancer Center
RECRUITING

Sunto-gun, Shizuoka, 411-8777, Japan
Swedish Cancer Institute Medical Oncology
RECRUITING

Seattle, Washington, 98104, United States
Taipei Veterans General Hospital
RECRUITING

Taipei, 11217, Taiwan
Texas Oncology Northeast Texas
RECRUITING

Tyler, Texas, 75702, United States
The First Affiliated Hospital Of Ningbo University
RECRUITING

Ningbo, Zhejiang, 315010, China
The First Affiliated Hospital of Nanchang University
RECRUITING

Nanchang, Jiangxi, 330209, China
The Second Attached Hospital Of Fujian Medical University
RECRUITING

Quanzhou, Fujian, 362002, China
Tianjin Cancer Hospital
RECRUITING

Tianjin, Tianjin Municipality, 300060, China
Tianjin Peoples Hospital
RECRUITING

Tianjin, Tianjin Municipality, 300121, China
Translational Research in Oncology US Inc, Trio Central Pharmacy
RECRUITING

Los Angeles, California, 90095, United States
US Oncology Research Investigational Products Center
RECRUITING

Irving, Texas, 75063, United States
Unidade Local de Saude de Matosinhos, EPE - Hospital Pedro Hispano
RECRUITING

Matosinhos Municipality, 4464-513, Portugal
United States Oncology Regulatory Affairs Corporate Office
RECRUITING

Nashville, Tennessee, 37203, United States
Universitaetsklinikum Dresden
RECRUITING

Dresden, 01307, Germany
Universitaetsklinikum Essen
RECRUITING

Essen, 45147, Germany
Universitaetsklinikum Krems
RECRUITING

Krems, 3500, Austria
Universitaetsklinikum Schleswig-Holstein - Kiel
RECRUITING

Kiel, 24105, Germany
Universitaetsklinikum Schleswig-Holstein - Luebeck
RECRUITING

Lübeck, 23538, Germany
Universitaetsklinikum Wuerzburg
RECRUITING

Würzburg, 97078, Germany
Universitaetsspital Basel
RECRUITING

Basel, 4052, Switzerland
Universitair Medisch Centrum Groningen
RECRUITING

Groningen, 9713 GZ, Netherlands
Universitair Ziekenhuis Leuven - Campus Gasthuisberg
RECRUITING

Leuven, 3000, Belgium
University Hospitals Cleveland Medical Center
RECRUITING

Cleveland, Ohio, 44106, United States
University of California Los Angeles
RECRUITING

Santa Monica, California, 90404, United States
University of Illinois Chicago
RECRUITING

Chicago, Illinois, 60612, United States
Uniwersyteckie Centrum Kliniczne
RECRUITING

Gdansk, 80-214, Poland
Virginia Cancer Specialists PC
RECRUITING

Fairfax, Virginia, 22031, United States
Wakayama Medical University Hospital
RECRUITING

Wakayama, Wakayama, 641-8510, Japan
West China Hospital of Sichuan University
RECRUITING

Chengdu, Sichuan, 611135, China
West Virginia University Health Sciences Center
RECRUITING

Morgantown, West Virginia, 26506, United States
Willamette Valley Cancer Institute and Research Center - Eugene
RECRUITING

Eugene, Oregon, 97401, United States
Yale New Haven Hospital
RECRUITING

New Haven, Connecticut, 06510, United States

Conditions

Explore the condition pages connected to this study.

EXTENSIVE STAGE SMALL CELL LUNG CANCER SMALL CELL LUNG CANCER