New hope for Tough-to-Treat lung cancer: targeted drug trial aims to outperform standard chemo

NCT ID NCT05048797

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This study is testing an experimental drug called trastuzumab deruxtecan against standard chemotherapy for people with advanced non-small cell lung cancer that has specific HER2 gene changes. It aims to see if the new drug helps patients live longer or live longer without their cancer getting worse. The trial will also measure side effects and how the treatment affects quality of life.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

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Anchorage, Alaska, 99508, United States
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Los Alamitos, California, 90720, United States
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Los Angeles, California, 90048, United States
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Orange, California, 92868, United States
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San Francisco, California, 94143, United States
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Santa Monica, California, 90404, United States
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Silver Spring, Maryland, 20910, United States
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Boston, Massachusetts, 02215, United States
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Ann Arbor, Michigan, 48109, United States
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Basking Ridge, New Jersey, 07920, United States
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Middletown, New Jersey, 07748, United States
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Montvale, New Jersey, 07645, United States
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New Brunswick, New Jersey, 08901, United States
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Commack, New York, 11725, United States
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Harrison, New York, 10604, United States
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New York, New York, 10065, United States
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Uniondale, New York, 11553, United States
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Pittsburgh, Pennsylvania, 15232, United States
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Dallas, Texas, 75246, United States
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Linz, 4020, Austria
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Vienna, 1210, Austria
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Ghent, 9000, Belgium
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Leuven, 3000, Belgium
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Barretos, 14784-400, Brazil
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Blumenau, 89010-340, Brazil
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Brasília, 70200-730, Brazil
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Natal, 59075-740, Brazil
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Salvador, 40170-110, Brazil
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São Paulo, 01321-001, Brazil
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São Paulo, 01327-001, Brazil
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Uberlândia, 38408-150, Brazil
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Vancouver, British Columbia, V5Z 4E6, Canada
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Brampton, Ontario, L6R 3J7, Canada
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Toronto, Ontario, M5G 1Z5, Canada
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Montreal, Quebec, H4A 3J1, Canada
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Beijing, 100142, China
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Beijing, 100730, China
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Changchun, 130021, China
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Changsha, 410008, China
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Changsha, 410013, China
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Chengdu, 610041, China
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Fuzhou, 350014, China
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Guangzhou, 510080, China
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Hangzhou, 310020, China
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Jinan, 250117, China
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Kunming, 650101, China
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Kunming, 650118, China
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Linhai, 317000, China
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Nanchang, 330006, China
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Nanjing, 210029, China
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Shanghai, 200032, China
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Shenyang, 110016, China
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Shenzhen, 518020, China
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Wenzhou, CN-325000, China
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Wuhan, 430022, China
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Xi'an, 710061, China
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Xiamen, 361003, China
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Yangzhou, 225001, China
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Vejle, 7100, Denmark
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Bordeaux, 33000, France
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Dijon, 21079, France
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Le Mans, 72037, France
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Lyon, 69373, France
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Marseille, 13915, France
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Nantes, 44093, France
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Toulouse, 31059, France
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Villejuif, 94805, France
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Cologne, 50937, Germany
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Dresden, 01307, Germany
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Mainz, 55131, Germany
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München, 81377, Germany
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Oldenburg, 26121, Germany
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Hong Kong, HKG, Hong Kong
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Hong Kong, Hong Kong
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Jordan, HKG, Hong Kong
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Bangalore, 560027, India
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Delhi, 110085, India
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Hyderabad, 500032, India
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Mumbai, 400012, India
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Nashik, 422002, India
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Milan, 20141, Italy
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Monza, 20090, Italy
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Orbassano, 10043, Italy
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Parma, 43100, Italy
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Roma, 00168, Italy
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Verona, 37126, Italy
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Chūōku, 104-0045, Japan
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Fukuoka, 812-8582, Japan
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Kashiwa, 277-8577, Japan
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Matsuyama, 791-0280, Japan
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Niigata, 951-8566, Japan
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Okayama, 700-8558, Japan
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Osaka, 541-8567, Japan
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Osakasayama-shi, 589-8511, Japan
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Sapporo, 060-8638, Japan
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Sendai, 980-0873, Japan
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Sunto-gun, 411-8777, Japan
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Yokohama, 241-8515, Japan
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Yonago-shi, 683-8504, Japan
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Mexico City, '14080, Mexico
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Mexico City, 03810, Mexico
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Amsterdam, 1081 HV, Netherlands
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Groningen, 9700 RB, Netherlands
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Nijmegen, 6525 GA, Netherlands
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Gdansk, 80-952, Poland
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Olsztyn, 10-357, Poland
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Przemyśl, 37-700, Poland
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Warsaw, 02-781, Poland
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Cheongju-si, 28644, South Korea
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Goyang-si, 10408, South Korea
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Gyeonggi-do, 13620, South Korea
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Seoul, 03080, South Korea
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Seoul, 05505, South Korea
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Seoul, 06351, South Korea
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L'Hospitalet de Llobregat, 08908, Spain
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Madrid, 28041, Spain
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Málaga, 29730, Spain
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Valencia, 46026, Spain
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Kaohsiung City, 833, Taiwan
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Taichung, 40201, Taiwan
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Taichung, 40705, Taiwan
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Tainan, 70403, Taiwan
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Taipei, 10048, Taiwan
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Taipei, 235, Taiwan
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Taipei, TAIWAN, Taiwan
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Taoyuan District, 333, Taiwan
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Çankaya, 06680, Turkey (Türkiye)
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Edirne, 22030, Turkey (Türkiye)
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Izmir, 35040, Turkey (Türkiye)
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Kadıkoy/Istanbul, 34722, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.

LOCALLY ADVANCED OR METASTATIC NON-SMALL CELL LUNG CANCER