First human tests begin for targeted fatty liver disease drug
NCT ID NCT05395481
Summary
This is an early-stage study to check the safety and side effects of a new drug called LY3849891 in people with fatty liver disease (MASLD) who have a specific genetic marker (PNPLA3 I148M). About 176 participants will receive injections of the drug, and researchers will use blood tests and MRI scans of the liver to see how the body processes the drug and if it reduces liver fat and inflammation. The study will last up to 32 weeks per person.
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Contacts and locations
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Locations
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Accel Research Sites - Maitland
Maitland, Florida, 32751, United States
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Advanced Pharma Clinical Research
Miami, Florida, 33175, United States
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Arizona Liver Health - Chandler
Chandler, Arizona, 85225, United States
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Charter Research - Winter Park
Orlando, Florida, 32803, United States
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Clinical Research Hospital Tokyo
Shinjuku-ku, 160-0004, Japan
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Clinical Trials of Texas, Inc.
San Antonio, Texas, 78229, United States
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Evolution Clinical Trials, Inc
Miami, Florida, 33122, United States
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FDI Clinical Research
San Juan, 00927, Puerto Rico
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Floridian Clinical Research
Miami Lakes, Florida, 33016, United States
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Houston Research Institute
Houston, Texas, 77079, United States
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IU Health University Hospital
Indianapolis, Indiana, 46290, United States
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Inland Empire Clinical Trials, LLC
Rialto, California, 92377, United States
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Orange County Research Center
Orange, California, 92868, United States
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P-One Clinic
Hachiōji, 192-0071, Japan
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Pinnacle Clinical Research
San Antonio, Texas, 78229, United States
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Synergy Healthcare LLC
Brandon, Florida, 33511, United States
Conditions
Explore the condition pages connected to this study.