New hope for kids with rare immune disorder: targeted drug added to standard chemotherapy

NCT ID NCT07431060

Summary

This study is testing if adding a new targeted drug called luvometinib to standard chemotherapy works better for children with a serious form of Langerhans cell histiocytosis (LCH), a rare immune system disorder. The trial will enroll 120 children across multiple hospitals and randomly assign them to receive either the standard treatment alone or the standard treatment plus luvometinib. The goal is to see if the combination leads to better long-term control of the disease with fewer relapses.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Hospital of Guizhou Medical University

    RECRUITING

    Guiyang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Anhui Provincial Children's Hospital

    RECRUITING

    Hefei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Jiangxi Provincial Children's Hospital

    RECRUITING

    Jiangxi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kunming Children's Hospital

    RECRUITING

    Kunming, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Xinjiang Medical University

    RECRUITING

    Ürümqi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital of Anhui Medical University

    RECRUITING

    Hefei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Affiliated Hospital of Guangxi Medical University

    RECRUITING

    Nanning, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Second Hospital, Sichuan University

    RECRUITING

    Chengdu, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xi'an Children's Hospital

    RECRUITING

    Xi'an, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Xi'an Northwest Women's and Children's Hospital

    RECRUITING

    Xi'an, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Zunyi Medical University Affiliated Hospital, Guizhou Provincial Children's Hospital

    RECRUITING

    Zunyi, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.