New drug combo aims to shrink tumors before surgery, kill remaining cells after

NCT ID NCT05775471

Summary

This study is testing a two-part treatment for high-risk cancer of the kidney's drainage system (upper tract urothelial carcinoma). It gives patients a combination of two immunotherapy drugs (pembrolizumab and enfortumab vedotin) before surgery to remove the kidney and ureter, aiming to shrink the tumor. After surgery, patients receive more pembrolizumab to try to kill any cancer cells left behind and prevent the cancer from coming back.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UCLA / Jonsson Comprehensive Cancer Center

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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