New hope for kids with rare bone disease: testing Next-Generation treatment

NCT ID NCT06079372

Summary

This study is testing a new drug called ALXN1850 against the current standard treatment (asfotase alfa) in children aged 2 to under 12 who have a rare bone-weakening condition called hypophosphatasia (HPP). The main goal is to see if the new drug is as safe and well-tolerated as the standard one. Researchers will also check if it helps improve bone health, walking ability, and motor skills.

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Contacts and locations

Locations

  • Research Site

    Hartford, Connecticut, 06106, United States

  • Research Site

    Baltimore, Maryland, 21287, United States

  • Research Site

    Minneapolis, Minnesota, 55455, United States

  • Research Site

    Kansas City, Missouri, 64108, United States

  • Research Site

    Durham, North Carolina, 27705, United States

  • Research Site

    Nashville, Tennessee, 37212, United States

  • Research Site

    Mar del Plata, B7600, Argentina

  • Research Site

    South Brisbane, 4101, Australia

  • Research Site

    Ottawa, Ontario, K1H 8L1, Canada

  • Research Site

    Bunkyō City, 113-8431, Japan

  • Research Site

    Minatoku, 105-8471, Japan

  • Research Site

    Suita-shi, 565-0871, Japan

  • Research Site

    Yonago-shi, 683-8504, Japan

  • Research Site

    Altındağ, 06230, Turkey (Türkiye)

  • Research Site

    Ankara, 06560, Turkey (Türkiye)

  • Research Site

    Edirne, 22030, Turkey (Türkiye)

  • Research Site

    Erzurum, 25240, Turkey (Türkiye)

  • Research Site

    Istanbul, 34899, Turkey (Türkiye)

  • Research Site

    Birmingham, B4 6NH, United Kingdom

  • Research Site

    Manchester, United Kingdom

  • Research Site

    Sheffield, S10 2TH, United Kingdom

Conditions

Explore the condition pages connected to this study.