Could a simpler pill regimen control HIV as well as complex therapies?

NCT ID NCT05502341

Ongoing Disease control Sponsor: Gilead Sciences Source: ClinicalTrials.gov ↗

Summary

This study is testing whether switching to a new two-drug combination (bictegravir plus lenacapavir) works as well as a person's current complex HIV medication regimen. It involves nearly 700 people whose HIV is already well-controlled. The main goal is to see if the new combination keeps the virus suppressed and is safe over 24 to 96 weeks.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

AIDS Arms, Inc., DBA Prism Health North Texas

Dallas, Texas, 75208, United States
ASL Città di Torino

Torino, 10149, Italy
ASST Fatebenefratelli Sacco

Milan, 20157, Italy
AXCES Research Group

Santa Fe, New Mexico, 87505, United States
Alfred Health

Melbourne, Victoria, 3004, Australia
Alta Bates Summit Medical Center, Summit Campus, East Bay Advanced Care

Oakland, California, 94609, United States
Atlanta ID Group

Atlanta, Georgia, 30309, United States
Azienda Ospedaliero-Universitaria di Modena

Modena, 40124, Italy
Barts Health NHS Trust

London, E1 1BB., United Kingdom
Be Well Medical Center

Berkeley, California, 48072, United States
Bios Clinical Research

Palm Springs, California, 92262, United States
Brighton and Sussex University Hospitals NHS Trust

Brighton, BN2 3EW, United Kingdom
CHU Nice-Hôpital l'Archet

Nice, 6202, France
Center Hospital of the National Center for Global Health and Medicine

Tokyo, 162-0052, Japan
Central Texas Clinical Research

Austin, Texas, 78705, United States
Chronic Viral Illness Service / McGill University Health Centre (MUHC)

Decarie Montreal, H4A 3J1, Canada
Chungnam National University Hospital

Daejeon, 35015, South Korea
Clinique Medicale du Quartier Latin

Montreal, H2L 0B1, Canada
Denver Health Medical Center

Denver, Colorado, 80204, United States
Department of HIV & Sexual Medicine

Birmingham, B9 5SS, United Kingdom
Desmond Tutu Health Foundation Clinical Trials Unit

Cape Town, 7925, South Africa
Diagnostic Clinic of Longview - Center for Clinical Research

Longview, Texas, 75605, United States
East Carolina University

Greenville, North Carolina, 27858, United States
Ezintsha

Johannesburg, 2193, South Africa
Far Eastern Memorial Hospital

New Taipei City, 22060, Taiwan
Floridian Clinical Research

Miami Lakes, Florida, 33016, United States
Fundación Huésped

Buenos Aires, 1202, Argentina
Gary Richmond, MD, PA, Inc.

Fort Lauderdale, Florida, 33316, United States
Gordon E. Crofoot MD PA

Houston, Texas, 77098, United States
Groupe Hospitalier Bichat Claude Bernard

Paris, 75018, France
HIV medicine and infectious diseases

London, SE5 9RS, United Kingdom
Helios Salud

Buenos Aires, 1425, Argentina
Holdsworth House Medical Practice

Sydney, New South Wales, 2010, Australia
Hope Clinical Research

San Juan, PR, 00909, Puerto Rico
Hospital Clinic Provincial de Barcelona

Barcelona, 08036, Spain
Hospital Clinico San Carlos

Madrid, 28040, Spain
Hospital General de Agudos J.M Ramon Mejia

Buenos Aires, 1072, Argentina
Hospital Ramon y Cajal, Madrid

Madrid, 28034, Spain
Hospital Saint Louis

Paris, 75010, France
Hospital Universitario La Paz

Madrid, 28046, Spain
Hospital Universitario Virgen del Rocio

Seville, 4103, Spain
Howard Brown Health Center

Chicago, Illinois, 60613, United States
Höpital de la Pitié Salpêtrière

Paris, 75651, France
ICH Study Center GmbH & Co. KG

Hamburg, 20146, Germany
ID Clinic

Regina, S4P 0W5, Canada
IRCCS Ospedale San Raffaele

Milan, 20127, Italy
Infektio Research GmbH & Co.KG

Frankfurt, 60596, Germany
Instituto Dominicano de Estudio Virologicos - IDEV

Santo Domingo, Dominican Republic
Istituto Nazionale Malattie Infettive "Lazzaro Spallanzani" IRCCS

Roma, 00149, Italy
Kansas City Care Clinic

Kansas City, Missouri, 64111, United States
Kaohsiung Medical University Chung-Ho Memorial Hospital

Kaohsiung City, 80756, Taiwan
Kaohsiung Medical University Chung-Ho Memorial Hospital

Kaohsiung City, 81362, Taiwan
Kyungpook National University Hospital

Daegu, 41944, South Korea
Lundquist Institute for Biomedical Innovation at Harbor - UCLA Medical Center

Torrance, California, 90502, United States
MVZ München am Goetheplatz

München, Germany
Maple Leaf Research

Toronto, M5G 1K2, Canada
Medical University of South Carolina (MUSC) Research NEXUS

Charleston, South Carolina, 29425, United States
Mercer University School of Medicine

Macon, Georgia, 31201, United States
Midland Florida Clinical Research Center, LLC

DeLand, Florida, 32720, United States
Midway Immunology & Research Center, LLC

Ft. Pierce, Florida, 34982, United States
National Hospital Organization Nagoya Medical Center

Nagoya, Japan
National Hospital Organization Osaka National Hospital

Osaka, 540-0006, Japan
New York Presbyterian Hospital

Flushing, New York, 11355, United States
North Texas Infectious Diseases Consultants

Dallas, Texas, 75246, United States
Orlando Immunology Center

Orlando, Florida, 32803, United States
Pacific Oaks Medical Group

Beverly Hills, California, 90211, United States
Peter Shalit, MD

Seattle, Washington, 98104, United States
Philadelphia FIGHT

Philadelphia, Pennsylvania, 19107, United States
Proyecto ACTU

San Juan, PR, 00935, Puerto Rico
Ricky K. Hsu, MD, PC

New York, New York, 10001, United States
Ruane Clinical Research Group, Inc

Los Angeles, California, 90036, United States
Saint Michael's Medical Center

Newark, New Jersey, 07102, United States
Schiff Center for liver Diseases/University of Miami

Miami, Florida, 33136, United States
Sefako Makgatho Health Sciences University

Ga-Rankuwa, 208, South Africa
Southampton Healthcare, Inc.

St Louis, Missouri, 63139, United States
Spectrum Health

Vancouver, V6Z 2T1, Canada
St. Hope Foundation

Bellaire, Texas, 77401, United States
St.Stephen's AIDS Trust, Clinical Trials Unit, 1st Floor, St.Stephen's Centre

London, SW109NH, United Kingdom
St.Vincent's Hospital Sydney

Darlinghurst, New South Wales, 2010, Australia
Taoyuan General Hospital

Taoyuan, 33004, Taiwan
Taylor Square Private Clinic

Darlinghurst, New South Wales, 2011, Australia
Texas Centers for Infectious Disease Associates

Fort Worth, Texas, 76104, United States
The Catholic University of Korea Seoul St. Mary's Hospital

Seoul, 06591, South Korea
The Men's Health Foundation

West Hollywood, California, 90046, United States
The Ottawa Hospital - General Campus

Ottawa, K1H 8L6, Canada
Therafirst Medical Centers

Fort Lauderdale, Florida, 33308, United States
Therapeutic Concepts, PA

Orlando, Florida, 32803, United States
Triple O Research Institute PA

West Palm Beach, Florida, 33407, United States
Universitatsklinikum Bonn

Bonn, 53127, Germany
University of California San Diego (UCSD)

San Diego, California, 92103, United States
University of North Carolina - Chapel Hill

Chapel Hill, North Carolina, 27514, United States
Yale University; School of Medicine; AIDS Program

New Haven, Connecticut, 06510, United States
Yonsei University Severance Hospital

Seoul, 03722, South Korea
zibp Zentrum für Infektiologie Berlin Prenzlauer Berg GmbH

Berlin, 10439, Germany

Conditions

Explore the condition pages connected to this study.

HIV-1-INFECTION