New hope for stomach cancer: experimental combo aims to wipe out tumors before surgery

NCT ID NCT07477444

Summary

This study is testing whether adding two new drugs (zanidatamab and tislelizumab) to standard chemotherapy before surgery is safe and more effective for people with HER2-positive stomach or esophageal cancer. The goal is to completely eliminate cancer cells in the tissue removed during surgery, which could lead to better long-term outcomes. The trial will enroll 29 patients with localized, operable cancer to first check safety and then measure how many patients achieve complete tumor disappearance.

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