Major trial launches for advanced stomach cancer: new drug combo challenges standard treatment

NCT ID NCT06764875

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

Summary

This large Phase 3 trial is testing whether a new combination of cancer drugs works better than current standard treatment for advanced HER2-positive stomach cancer. The study will enroll 840 patients with previously untreated, advanced stomach or gastroesophageal junction cancer. Researchers will compare how long patients live without their cancer worsening and monitor side effects across three different treatment groups.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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Anchorage, Alaska, 99508, United States
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Phoenix, Arizona, 85054, United States
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Duarte, California, 91010, United States
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La Jolla, California, 92037, United States
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Los Alamitos, California, 90720, United States
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Los Angeles, California, 90089, United States
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Santa Monica, California, 90404, United States
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Solvang, California, 93463, United States
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Upland, California, 91786, United States
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Walnut Creek, California, 94598, United States
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Aurora, Colorado, 80045, United States
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Jacksonville, Florida, 32224, United States
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Orlando, Florida, 32806, United States
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Marietta, Georgia, 30060, United States
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Chicago, Illinois, 60612, United States
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NOT_YET_RECRUITING

Chicago, Illinois, 60637, United States
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Evanston, Illinois, 60201, United States
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Hinsdale, Illinois, 60521, United States
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Niles, Illinois, 60714, United States
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Dyer, Indiana, 46311, United States
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Louisville, Kentucky, 40217, United States
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Silver Spring, Maryland, 20904, United States
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Boston, Massachusetts, 02114, United States
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Boston, Massachusetts, 02118, United States
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NOT_YET_RECRUITING

Detroit, Michigan, 48202, United States
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Grand Rapids, Michigan, 49503, United States
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Burnsville, Minnesota, 55337, United States
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Kansas City, Missouri, 64111, United States
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St Louis, Missouri, 63108, United States
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NOT_YET_RECRUITING

Omaha, Nebraska, 68198-5885, United States
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Reno, Nevada, 89502, United States
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Summit, New Jersey, 07901, United States
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Santa Fe, New Mexico, 87505, United States
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New Hyde Park, New York, 11042, United States
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New York, New York, 10021, United States
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Cincinnati, Ohio, 45220, United States
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NOT_YET_RECRUITING

Columbus, Ohio, 43210, United States
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Philadelphia, Pennsylvania, 19104, United States
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Knoxville, Tennessee, 37909, United States
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Nashville, Tennessee, 37232, United States
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Dallas, Texas, 75246, United States
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Webster, Texas, 77598, United States
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Charlottesville, Virginia, 22908, United States
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Fairfax, Virginia, 22031, United States
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Fairfax, Virginia, 22031, United States
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Richmond, Virginia, 23235, United States
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NOT_YET_RECRUITING

Charleston, West Virginia, 25304, United States
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Madison, Wisconsin, 53792, United States
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Buenos Aires, 1264, Argentina
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Ciudad Autónoma Buenos Aires, C1430EFA, Argentina
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Ciudad de Buenos Aires, 1280, Argentina
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Rosario, 2123, Argentina
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Rosario, S2000DEJ, Argentina
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Viedma, R8500ACE, Argentina
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Darlinghurst, 2010, Australia
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Heidelberg, 3084, Australia
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Murdoch, 6150, Australia
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Westmead, 2145, Australia
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Linz, 4010, Austria
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Salzburg, 5020, Austria
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Vienna, 1090, Austria
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NOT_YET_RECRUITING

Wiener Neustadt, 2700, Austria
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Edegem, 2650, Belgium
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Ghent, 9000, Belgium
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Leuven, 3000, Belgium
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Liège, 4000, Belgium
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Barretos, 14784-057, Brazil
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Brasília, 71681-603, Brazil
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Campo Grande, 79020-180, Brazil
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Natal, 59075-740, Brazil
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Porto Alegre, 91350-200, Brazil
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Recife, 50040-000, Brazil
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Salvador, 40170-110, Brazil
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São Paulo, 05652-9000, Brazil
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Vitória, 29043-272, Brazil
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Calgary, Alberta, T2N 5G2, Canada
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NOT_YET_RECRUITING

Edmonton, Alberta, T6G 1Z2, Canada
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Winnipeg, Manitoba, R3E 0V9, Canada
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Barrie, Ontario, L4M 6M2, Canada
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Brampton, Ontario, L6R 3J9, Canada
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Hamilton, Ontario, L8V 5C2, Canada
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Toronto, Ontario, M5G 2M9, Canada
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Chicoutimi, Quebec, G7H 5H6, Canada
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Montreal, Quebec, H3A 1A1, Canada
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Port Montt, 5480000, Chile
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Rancagua, 2852424, Chile
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Santiago, 7500653, Chile
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Santiago, 7620002, Chile
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Santiago, 8241479, Chile
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Temuco, 4810218, Chile
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NOT_YET_RECRUITING

Viña del Mar, 2520598, Chile
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Anyang, 455000, China
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Beijing, 100050, China
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Beijing, CN-100730, China
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Bengbu, 233004, China
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Changchun, 130021, China
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Changsha, 410013, China
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Chengdu, 610041, China
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Fuzhou, 350001, China
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Fuzhou, 350014, China
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Guangzhou, 510060, China
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Guangzhou, 510655, China
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Guangzhou, 510700, China
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Hangzhou, 310016, China
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Harbin, 150081, China
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Hefei, 230022, China
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Hefei, 230031, China
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Jinan, 250021, China
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Kunming, 650118, China
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Lanzhou, 730000, China
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Linfen, 041099, China
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Linyi, 276001, China
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Nanchang, 330008, China
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Nanjing, 210009, China
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Nanjing, 210029, China
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Shandong, China
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Shanghai, 200025, China
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Shanghai, 200032, China
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Shanghai, 201114, China
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Shenyang, 110004, China
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Shenyang, 110042, China
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Shijiazhuang, 050000, China
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Tianjin, 300060, China
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Wenzhou, 325000, China
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Wuhan, 430030, China
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Xi'an, 710061, China
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Xi'an, 710068, China
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Xining, 810001, China
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Yinchuan, 750004, China
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Zhengzhou, 450008, China
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NOT_YET_RECRUITING

Bordeaux, 33076, France
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Caen, 14000, France
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Clermont-Ferrand, 63003, France
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Dijon, 21079, France
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Lyon, 69373, France
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Marseille, 13273, France
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Poitiers, 86021, France
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Rennes, 35000, France
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Toulouse, 31059, France
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Villejuif, 94805, France
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Augsburg, 86156, Germany
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Bad Saarow, 15526, Germany
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Berlin, 10249, Germany
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Berlin, 10707, Germany
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Berlin, 13353, Germany
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Braunschweig, 38114, Germany
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Chemnitz, 9116, Germany
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Düsseldorf, 40225, Germany
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Essen, 45122, Germany
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Frankfurt, 60488, Germany
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Göttingen, 37075, Germany
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Hamburg, 20246, Germany
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Leipzig, 04103, Germany
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Ludwigshafen, 67063, Germany
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Mannheim, 68167, Germany
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Ulm, 89081, Germany
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Hong Kong, 150001, Hong Kong
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Hong Kong, 999077, Hong Kong
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Hong Kong, Hong Kong
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Hong Kong, Hong Kong
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NOT_YET_RECRUITING

Shatin, 00000, Hong Kong
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Budapest, 1083, Hungary
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Budapest, 1122, Hungary
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Budapest, 1145, Hungary
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Gyöngyös, 3200, Hungary
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NOT_YET_RECRUITING

Győr, 9024, Hungary
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Gyula, 5700, Hungary
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Zalaegerszeg, 8900, Hungary
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NOT_YET_RECRUITING

Ansārinagar, 110 029, India
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NOT_YET_RECRUITING

Bangalore, 560027, India
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NOT_YET_RECRUITING

Delhi, 110029, India
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Delhi, 110085, India
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Hyderabad, 500034, India
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Kolkata, 700094, India
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Mumbai, 400012, India
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NOT_YET_RECRUITING

Varanasi, 221005, India
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Cagliari, 09124, Italy
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Florence, 50134, Italy
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Milan, 20162, Italy
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Naples, 80131, Italy
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Padua, 35128, Italy
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Rozzano, 20089, Italy
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Torino, 10126, Italy
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Tricase, 73039, Italy
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Akashi-shi, 673-8558, Japan
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Bunkyō City, 113-8677, Japan
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Chūōku, 104-0045, Japan
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Fukuoka, 811-1395, Japan
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Fukuoka, 812-8582, Japan
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Hidaka-shi, 350-1298, Japan
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Hirakata-shi, 573-1191, Japan
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Hiroshima, 730-8518, Japan
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Kasama-shi, 309-1793, Japan
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Kita-gun, 761-0793, Japan
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Kitaadachi-gun, 362-0806, Japan
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Kōtoku, 135-8550, Japan
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Matsuyama, 791-0280, Japan
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Niigata, 951-8566, Japan
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Osaka, 541-8567, Japan
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Osakasayama-shi, 589-8511, Japan
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Ota-shi, 373-8550, Japan
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Sakaishi, 591-8025, Japan
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Sendai, 980-8574, Japan
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Shiwa-gun, 028-3695, Japan
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Suita-shi, 565-0871, Japan
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Sunto-gun, 411-8777, Japan
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Toyoake-shi, 470-1192, Japan
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Yokohama, 232-0024, Japan
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Yokohama, 241-8515, Japan
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George Town, 10450, Malaysia
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Ipoh, 30450, Malaysia
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Kuala Lumpur, 50586, Malaysia
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Kuala Lumpur, 59100, Malaysia
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Sabak Bernam, 88996, Malaysia
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Amsterdam, 1081 HV, Netherlands
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Arnhem, 6815 AD, Netherlands
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NOT_YET_RECRUITING

Leiden, 2333 ZA, Netherlands
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NOT_YET_RECRUITING

Arequipa, AREQUIPA54, Peru
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NOT_YET_RECRUITING

Callao, CALLAO 02, Peru
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Lima, 15036, Peru
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Lima, LIMA 29, Peru
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Lima, Lima 34, Peru
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Lima, Lima39, Peru
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NOT_YET_RECRUITING

San Isidro, 15073, Peru
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Bialystok, 15-027, Poland
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Gdansk, 80-219, Poland
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Koszalin, 75-581, Poland
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Olsztyn, 10-228, Poland
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Przemyśl, 37-700, Poland
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Warsaw, 02-034, Poland
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Wroclaw, 50-556, Poland
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Rio Piedras, 00935, Puerto Rico
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Daegu, 41404, South Korea
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Goyang-si, 410-769, South Korea
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Gyeonggi-do, 13620, South Korea
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Jeonnam, 519-763, South Korea
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Seoul, 03080, South Korea
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Seoul, 03722, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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Seoul, 5505, South Korea
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Badalona, 08916, Spain
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Barcelona, 08035, Spain
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Madrid, 28034, Spain
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Madrid, 28041, Spain
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Ourense, 32005, Spain
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Santander, 39008, Spain
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Seville, 41013, Spain
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Valencia, 46010, Spain
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Kaohsiung City, 80756, Taiwan
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Kaohsiung City, 824, Taiwan
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Taichung, 40447, Taiwan
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Taichung, Taiwan
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Tainan, 704, Taiwan
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Tainan, 736, Taiwan
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Taipei, 100, Taiwan
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Taipei, 112, Taiwan
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Taoyuan District, 333, Taiwan
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Bangkok, 10330, Thailand
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Bangkok, 10400, Thailand
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Bangkok, 10700, Thailand
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Banphaeo, 74120, Thailand
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Dusit, 10300, Thailand
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Khon Kaen, 40002, Thailand
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Muang, 22000, Thailand
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Ankara, 06100, Turkey (Türkiye)
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Antalya, 07100, Turkey (Türkiye)
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Diyarbakır, 21280, Turkey (Türkiye)
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Erzurum, 25240, Turkey (Türkiye)
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Istanbul, 34010, Turkey (Türkiye)
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NOT_YET_RECRUITING

Izmir, 35965, Turkey (Türkiye)
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Mezitli, 33200, Turkey (Türkiye)
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Cambridge, CB2 2QQ, United Kingdom
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Coventry, CV2 2DX, United Kingdom
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Dundee, DD1 9SY, United Kingdom
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London, EC1A 7BE, United Kingdom
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London, W1G 6AD, United Kingdom
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Manchester, M20 4BX, United Kingdom
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Sutton, SM2 5PT, United Kingdom
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Hanoi, 100000, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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Hồ Chí Minh, 700000, Vietnam
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Việt Trì, 35000, Vietnam
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Vinh, 460000, Vietnam

Conditions

Explore the condition pages connected to this study.

GASTROESOPHAGEAL JUNCTION ADENOCARCINOMA HER2-POSITIVE GASTRIC CANCER