New hope for stem cell transplant patients with severe GVHD

NCT ID NCT07509749

First seen Apr 05, 2026 · Last updated Jun 13, 2026 · Updated 11 times

Summary

This study tests whether adding the drug ruxolitinib to standard steroids works better than steroids alone for treating severe graft-versus-host disease (GVHD) after a stem cell transplant. About 54 adults who develop severe GVHD within 100 days of their first transplant will take part. The main goal is to see if the combination improves response at 28 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Hematology, the Fifth Center of Chinese PLA General Hospital

    RECRUITING

    Beijing, 100853, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

disease related to hematopoietic stem cell transplant graft versus host disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.