New hope for stem cell transplant patients: drug combo targets deadly GVHD

NCT ID NCT07509749

First seen Apr 05, 2026 · Last updated May 06, 2026 · Updated 5 times

Summary

This study tests whether adding ruxolitinib to standard steroids helps control severe graft-versus-host disease (GVHD) after a stem cell transplant. About 54 adults who develop severe GVHD within 100 days of their first transplant will receive the combination therapy. The goal is to see if more patients improve by day 28 and stay better for longer.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Hematology, the Fifth Center of Chinese PLA General Hospital

    RECRUITING

    Beijing, 100853, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.