New hope for young patients with spreading bone cancer

NCT ID NCT06820957

Summary

This trial is testing whether adding two new drugs, irinotecan and regorafenib, to standard chemotherapy works better for young patients with Ewing sarcoma that has spread. It aims to see if this combination helps patients live longer without their cancer returning. The study is for patients aged 1 to 50 who are newly diagnosed with this rare and aggressive cancer.

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Contacts and locations

Locations

  • BI-LO Charities Children's Cancer Center

    Greenville, South Carolina, 29605, United States

  • Children's Hospital of Alabama

    Birmingham, Alabama, 35233, United States

  • East Tennessee Childrens Hospital

    Knoxville, Tennessee, 37916, United States

  • Kapiolani Medical Center for Women and Children

    Honolulu, Hawaii, 96826, United States

  • Lurie Children's Hospital-Chicago

    Chicago, Illinois, 60611, United States

  • NYU Langone Hospital - Long Island

    Mineola, New York, 11501, United States

  • Prisma Health Richland Hospital

    Columbia, South Carolina, 29203, United States

  • Saint Christopher's Hospital for Children

    Philadelphia, Pennsylvania, 19134, United States

  • Saint Jude Midwest Affiliate

    Peoria, Illinois, 61637, United States

Conditions

Explore the condition pages connected to this study.