Hope for kids with advanced bone cancer: new combo trial launches
NCT ID NCT06820957
First seen Nov 01, 2025 · Last updated May 05, 2026 · Updated 29 times
Summary
This study tests whether adding three drugs (vincristine, irinotecan, and regorafenib) to standard chemotherapy helps people with metastatic Ewing sarcoma live longer without the cancer growing. About 437 participants aged 1 to 50 with newly diagnosed, spread cancer will be randomly assigned to the new combo or standard treatment. The goal is to see if the new approach is more effective at controlling the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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BI-LO Charities Children's Cancer Center
Greenville, South Carolina, 29605, United States
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Children's Hospital of Alabama
Birmingham, Alabama, 35233, United States
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East Tennessee Childrens Hospital
Knoxville, Tennessee, 37916, United States
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Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, 96826, United States
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Lurie Children's Hospital-Chicago
Chicago, Illinois, 60611, United States
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NYU Langone Hospital - Long Island
Mineola, New York, 11501, United States
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Prisma Health Richland Hospital
Columbia, South Carolina, 29203, United States
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Saint Christopher's Hospital for Children
Philadelphia, Pennsylvania, 19134, United States
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Saint Jude Midwest Affiliate
Peoria, Illinois, 61637, United States
Conditions
Explore the condition pages connected to this study.