New Triple-Drug attack on tough endometrial cancer begins testing

NCT ID NCT07318324

Summary

This early-phase study aims to find a safe and effective dose of a three-drug combination (avutometinib, defactinib, and everolimus) for people with recurrent endometrial cancer that has specific genetic changes in the RAS pathway. It will enroll about 31 participants who have already tried other treatments, including immunotherapy. The main goals are to determine the best dose for future studies and to closely monitor the safety and side effects of this new combination.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.