New drug aims to zap leg clots faster

NCT ID NCT06149520

Summary

This study tested if a new drug, BAY 3018250, could dissolve dangerous leg blood clots (deep vein thrombosis) faster and more effectively than standard blood thinners. 258 adults with recent leg clots received either a single dose of the new drug or a placebo, alongside their usual blood thinners. Researchers used ultrasounds to measure clot size and tracked safety for 90 days to see if the drug worked better and was safe.

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Contacts and locations

Locations

  • AP-HP Hopital Europeen Georges-Pompidou (HEGP) - Service de medecine vasculaire

    Paris, 75908, France

  • ASST dei Sette Laghi | Ospedale Di Circolo e Fondazione Macchi Di Varese - Centro Trombosi ed Emostasi

    Varese, 21100, Italy

  • AULSS N. 2 Marca Trevigiana_Ospedale di Treviso - UOC Pronto Soccorso

    Treviso, 31100, Italy

  • AZ Groeninge - Campus Kennedylaan

    Kortrijk, 8500, Belgium

  • AZ Sint-Maarten

    Mechelen, 2800, Belgium

  • Albert Schweitzer Hospital | Internal Medicine - Hematology Department

    Dordrecht, 3318 AT, Netherlands

  • Ankara Bilkent Sehir Hastanesi

    Bilkent Ankara, 6800, Turkey (Türkiye)

  • Azienda Ospedale-Università di Padova - Medicina Generale ad indirizzo trombotico-emorragico

    Padua, 35128, Italy

  • Azienda Ospedaliero-Universitaria Di Bologna IRCCS_Policlinico Sant'Orsola - Angiologia e Malattie della Coagulazione

    Bologna, 40138, Italy

  • Azienda Unita Locale Socio Sanitaria 2 Marca Trevigiana | Castelfranco Veneto Hospital - Angiologia Department

    Castelfranco Veneto, <unknown>, Italy

  • Azienda Unita Sanitaria Locale di Reggio Emilia | Arcispedale Santa Maria Nuova - Cardiovascular Medicine

    Reggio Emilia, 42122, Italy

  • Bekes Varmegyei Kozponti Korhaz - Dr. Rethy Pal Tagkorhaz

    Békéscsaba, 5600, Hungary

  • Centre Hospitalier Regional Universitaire (CHRU) Brest - Hopital de la Cavale Blanche

    Brest, 29609, France

  • Centre Hospitalier Universitaire (CHU) de Saint-Etienne - Hopital Nord

    Saint-Etienne, 42000, France

  • Centre Hospitalier Universitaire (CHU) de Toulouse - Hopital de Rangueil - Service de medecine vasculaire

    Toulouse, 31059, France

  • Centre Hospitalier Universitaire Amiens Picardie Site Sud

    Amiens Cedex1, 80054, France

  • Centre Hospitalier Universitaire Grenoble Alpes (CHU Grenoble Alpes) - Hopital Albert Michallon

    La Tronche, 38700, France

  • Centre Hospitalier Universitaire de Clermont Ferrand - Gabriel Montpied

    Clermont-Ferrand, 63003, France

  • Erciyes Universitesi Tip Fakultesi

    Kayseri, 38039, Turkey (Türkiye)

  • Fejer Varmegyei Szent Gyorgy Egyetemi Oktato Korhaz - II. Belgyogyaszat

    Székesfehérvár, 8000, Hungary

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS - UOSD Malattie Emorragiche e Trombotiche

    Roma, 00168, Italy

  • General Hospital Of Athens G Gennimatas- Department of Vascular Surgery

    Athens, 115 27, Greece

  • General Hospital Of Thessaloniki Papageorgiou- 1st Department of Surgery

    Efkarpia, 564 29, Greece

  • General University Hospital Of Patras- Department of Vascular Surgery

    Pátrai, 265 04, Greece

  • Hopitaux Universitaires de Strasbourg - Le Nouvel Hopital Civil (NHC)

    Strasbourg, 67091, France

  • Hospital Universitari De Girona Doctor Josep Trueta | Medicina Interna

    Girona, 17007, Spain

  • Hospital Universitario Infanta Sofia | Medicina Interna

    San Sebastián de los Reyes, Madrid, 28702, Spain

  • Hospitale, s.r.o. - Interné oddelenie

    Šahy, 936 01, Slovakia

  • Humanitas Mirasole S.p.A. - Centro Trombosi e Malattie Emorragiche

    Rozzano, 20089, Italy

  • Hôpital Louis Mourier - Colombes Cedex

    Colombes, 92701, France

  • Hôpital Sainte Musse

    Toulon, 83100, France

  • Imelda - Vascular Surgery Dept

    Bonheiden, 2820, Belgium

  • Interni a kardiologicka ambulance, Nemocnice Znojmo, prispevkova organizace

    Znojmo, 669 02, Czechia

  • Interni oddeleni, Krnovska nemocnice, Sdruzene zdravotnicke zarizeni Krnov, prispevkova organizace

    Krnov, 794 01, Czechia

  • Istanbul Universitesi Cerrahpasa-Cerrahpasa Tip Fakultesi

    Istanbul, 34098, Turkey (Türkiye)

  • Izmir Sehir Hastanesi

    Izmir, 35540, Turkey (Türkiye)

  • Kardiocentrum AGEL a.s. - Angiologické oddelenie

    Košice, 040 15, Slovakia

  • Kardiologicka klinika, Fakultni nemocnice Kralovske Vinohrady

    Prague, 100 34, Czechia

  • Katholieke Universiteit Leuven (KU Leuven) - Center for Molecular and Vascular Biology (CMVB)

    Leuven, 3000, Belgium

  • Kistarcsai Flor Ferenc Korház - II. Belgyógyászat - Angiológia

    Kistarcsa, 2143, Hungary

  • LMU Klinikum Campus Innenstadt | Medizinische Klinik und Poliklinik IV | FB Angiologie

    München, 80336, Germany

  • Leids Universitair Medisch Centrum (LUMC) (Leiden University Medical Center)

    Leiden, 2300 RC, Netherlands

  • McGill University Health Centre - Glen Site

    Montreal, Quebec, H4A 3J1, Canada

  • Medical Institute Ministry of Interior

    Sofia, 1606, Bulgaria

  • Multiprofile Hospital for Active Treatment Dr. Stefan Cherkezov | Base 1 - Cardiology Department

    Veliko Tarnovo, 5000, Bulgaria

  • Nemocnice Roudnice nad Labem - interni oddeleni

    Roudnice nad Labem, 41301, Czechia

  • Nemocnicná a.s. - Interné oddelenie

    Malacky, 901 22, Slovakia

  • Penta Hospitals | Hospital and Polyclinic Spisska Nova Ves - Internal Medicine Department

    Spišská Nová Ves, 052 01, Slovakia

  • Penta Hospitals | Zeleznicna Nemocnica Kosice - Angiologicka ambulancia

    Košice, 040 01, Slovakia

  • Saglik Bilimleri Üniversitesi Dr. Siyami Ersek Gögüs Kalp ve Damar Cerrahisi Egitim Ve Arastirma Hastanesi

    Istanbul, 34744, Turkey (Türkiye)

  • Semmelweis Egyetem - Belgyógyászati és Hematológiai Klinika, Kardiológia

    Budapest, 1088, Hungary

  • Somogy Varmegyei Kaposi Mor Oktato Korhaz - Általános Belgyógyászati Osztály

    Kaposvár, 7400, Hungary

  • Specialized Hospital For Active Cardiology Treatment Medica Kor EAD

    Rousse, 7013, Bulgaria

  • Szegedi Tudományegyetem, Szent-Györgyi Albert Klinikai Központ - Belgyógyászati Klinika

    Szeged, 6725, Hungary

  • UNIVERSITAETSKLINIKUM FREIBURG - Universitaets-Herzzentrum Bad Krozingen | Klinik für Kardiologie und Angiologie

    Bad Krozingen, 79189, Germany

  • UZ Gent

    Ghent, 9000, Belgium

  • Universitaetsklinikum Carl Gustav Carus an der Technischen Universitaet Dresden | Medizinische Klinik I - FB Haemostaseologie

    Dresden, 01307, Germany

  • Universitaetsklinikum Muenster | Klinik fuer Kardiologie I Sektion Angiologie

    Münster, 48149 Münster, Germany

  • Universiteit Ziekenhuis Antwerpen | Thoraxheelkunde Afdeling

    Antwerp, 2650, Belgium

  • University General Hospital Attikon - 1st Department of Vascular surgery University of Athens

    Athens, 124 62, Greece

  • University General Hospital Of Ioannina- Department of Surgery, Vascular Unit Faculty

    Ioannina, 455 00, Greece

  • University Multiprofile Hospital For Active Treatment 'Alexandrovska' EAD

    Sofia, 1431, Bulgaria

  • University Multiprofile Hospital For Active Treatment Kanev AD

    Rousse, 7002, Bulgaria

  • University Multiprofile Hospital for Active Treatment 'Sveta Ekaterina' EAD, Sofia

    Sofia, 1431, Bulgaria

  • Vojenská nemocnice Brno - Interní oddelení, pododbor kardiologie

    Brno, 615 00, Czechia

  • Všeobecná fakultní nemocnice v Praze - II. interní klinika - klinika kardiologie a angiologie, AJIP

    Prague, 128 08, Czechia

  • Ziekenhuis Oost-Limburg | Genk, Sint-Jan campus - Thoracic Vascular Surgery Department

    Genk, 3600, Belgium

  • Zuyderland Medical Centre | Internal Medicine Department

    Geleen, 6162 BG, Netherlands

Conditions

Explore the condition pages connected to this study.