New shot aims to tame toxic iron in blood disorder

NCT ID NCT06421636

Recruiting now Disease control Sponsor: Regeneron Pharmaceuticals Source: ClinicalTrials.gov ↗

Summary

This study is testing an experimental drug called REGN7999, given as an injection under the skin, for people with a genetic blood disorder called non-transfusion dependent beta-thalassemia. The main goal is to see if the drug can safely reduce dangerously high levels of iron that build up in the body, particularly in the liver. Researchers will compare the drug's effects against a placebo in about 95 participants to measure changes in iron levels and monitor for side effects.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

All India Institute of Medical Sciences, New Delhi
RECRUITING

New Delhi, National Capital Territory of Delhi, 110029, India
Amrita Institute of Medical Sciences and Research Centre (AIMS)
RECRUITING

Kochi, Kerala, 682041, India
Chiang Mai University
RECRUITING

Chiang Mai, 50200, Thailand
Children's Hospital Agia Sophia
RECRUITING

Athens, Attica, 11521, Greece
Chulalongkorn University
RECRUITING

Bangkok, 10330, Thailand
Day Hospital Thalassemia and Haemoglobinopathies (DHTE); A.O.U S.Anna
RECRUITING

Ferrara, 44124, Italy
Hacettepe University
RECRUITING

Ankara, 06100, Turkey (Türkiye)
Hemato-Oncology Clinic Ahmedabad PVT. LTD.
RECRUITING

Ahmedabad, Gujarat, 380009, India
Hospital Ampang
RECRUITING

Ampang, Selangor, 68000, Malaysia
Hospital Queen Elizabeth
RECRUITING

Kota Kinabalu, Sabah, 88586, Malaysia
Hospital Tunku Ampuan Besar Tuanku Aishah Rohani (HPKK UKM)
RECRUITING

Kuala Lumpur, 56000, Malaysia
Imperial College Healthcare NHS Trust
RECRUITING

London, W12 0HS, United Kingdom
Indraprastha Apollo Hospitals
RECRUITING

New Delhi, National Capital Territory of Delhi, 110048, India
JK Lon Hospital
RECRUITING

Jaipur, Rajasthan, 302004, India
K Eristavi National Center of Experimental and Clinical Surgery
RECRUITING

Tbilisi, 0159, Georgia
K J Somaiya Super Specialty Hospital & Research Centre
RECRUITING

Mumbai, Maharashtra, 400022, India
Laiko General Hospital of Athens
RECRUITING

Athens, Attica, 11527, Greece
Medinvest Institute of Hematology and Transfusiology Limited
RECRUITING

Tbilisi, 0160, Georgia
Nirmal Hospital Pvt. Ltd - Surat
RECRUITING

Surat, Gujarat, 395002, India
Phramongkutklao Hospital
RECRUITING

Bangkok, 10400, Thailand
Sarawak General Hospital
RECRUITING

Kuching, Sarawak, 93586, Malaysia
Songklanagarind Hospital, Prince of Songkla University
RECRUITING

Hat Yai, Changwat Songkhla, 90110, Thailand
Srinagarind Hospital
RECRUITING

Khon Kaen, 40000, Thailand
University College London Hospitals NHS Trust
RECRUITING

London, NW1 2PG, United Kingdom
University Hospital of Ioannina
RECRUITING

Ioannina, 45110, Greece
Weill Cornell Medicine
RECRUITING

New York, New York, 10065, United States

Conditions

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NON-TRANSFUSION DEPENDENT BETA-THALASSEMIA (NTDT)