First human test of Triple-Threat cancer drug cocktail

NCT ID NCT01829568

Summary

This early-stage study aims to find the safest and most effective doses of two oral drugs, lenalidomide and ibrutinib, when given alongside the standard antibody drug rituximab. It involves 33 adults with previously untreated stage II-IV follicular lymphoma, a type of slow-growing blood cancer. The main goal is to understand the side effects and determine the best doses for future research, not to cure the disease.

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Contacts and locations

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

  • NYP/Weill Cornell Medical Center

    New York, New York, 10065, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

  • Roswell Park Cancer Institute

    Buffalo, New York, 14263, United States

  • UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27599, United States

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois, 60637, United States

Conditions

Explore the condition pages connected to this study.