Hope for rare lung cancer: new combo trial launches

NCT ID NCT07476287

First seen Mar 17, 2026 · Last updated Jun 13, 2026 · Updated 12 times

Summary

This study tests a new medicine (PF-08634404) given with chemotherapy for adults with transformed small cell lung cancer, a rare and aggressive cancer that develops after other treatments stop working. About 40 participants who have not yet been treated for this cancer type will receive the drug combination through IV infusions. The goal is to see if the combination shrinks tumors and to monitor any side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope Lennar Foundation Cancer Center

    RECRUITING

    Irvine, California, 92618, United States

  • City of Hope National Medical Center

    RECRUITING

    Duarte, California, 91010, United States

  • Hope and Healing Clinical Research

    RECRUITING

    Hinsdale, Illinois, 60521, United States

  • Hope and Healing Clinical Research

    RECRUITING

    New Lenox, Illinois, 60451, United States

  • Japanese Foundation for Cancer Research

    RECRUITING

    Kotoku, Tokyo, 135-8550, Japan

  • National Cheng Kung University Hospital

    NOT_YET_RECRUITING

    Tainan, 704302, Taiwan

  • National Taiwan University Hospital

    NOT_YET_RECRUITING

    Taipei, 100, Taiwan

  • Peking Union Medical College Hospital

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100730, China

  • Shaare Zedek Medical Center

    RECRUITING

    Jerusalem, Jerusalem, 9103102, Israel

  • Shanghai Chest Hospital

    NOT_YET_RECRUITING

    Shanghai, Shanghai Municipality, 200030, China

  • Sheba Medical Center

    RECRUITING

    Ramat Gan, HA Merkaz, 5265601, Israel

  • Union Hospital Tongji Medical College Huazhong University of Science and Technology

    NOT_YET_RECRUITING

    Wuhan, Hubei, 430048, China

Conditions

Explore the condition pages connected to this study.