New hope for stomach cancer: experimental drug combo trial opens
NCT ID NCT06469944
First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This study tests new experimental drugs combined with standard chemotherapy and immunotherapy for people with advanced stomach, gastroesophageal junction, or esophageal cancer that cannot be removed by surgery or has spread. About 160 participants will receive the combination to see if it is safe and helps shrink tumors. The goal is to find better treatment options for this hard-to-treat cancer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Asan Medical Center-Department of Oncology ( Site 5901)
RECRUITINGSeoul, 05505, South Korea
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Azienda Ospedaliero Universitaria Pisana ( Site 5206)
RECRUITINGPisa, Tuscany, 56126, Italy
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Beijing Cancer hospital-Digestive Oncology ( Site 5500)
RECRUITINGBeijing, Beijing Municipality, 100142, China
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Bradford Hill Norte ( Site 6407)
RECRUITINGAntofagasta, 1263521, Chile
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Bradfordhill-Clinical Area ( Site 6401)
RECRUITINGSantiago, Region M. de Santiago, 8420383, Chile
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CHU-BREST Cavale Blanche ( Site 5104)
RECRUITINGBrest, Finistere, 29200, France
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CIC. ( Site 5100)
RECRUITINGLille, Nord, 59037, France
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Centro de Investigación del Maule ( Site 6408)
RECRUITINGTalca, Maule Region, 3481349, Chile
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Centro de Oncología de Precisión-Oncology ( Site 6404)
RECRUITINGSantiago, Region M. de Santiago, 7560908, Chile
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China Medical University Hospital ( Site 6007)
RECRUITINGTaichung, 404, Taiwan
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Chulalongkorn Hospital ( Site 6104)
RECRUITINGPathumwan, Bangkok, 10330, Thailand
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Clínica Puerto Montt ( Site 6409)
RECRUITINGPort Montt, Los Lagos Region, 5500243, Chile
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Clínica UC San Carlos de Apoquindo ( Site 6405)
RECRUITINGSantiago, Region M. de Santiago, 7620002, Chile
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Columbia University Irving Medical Center-CUIMC Herbert Irving Comprehensive Cancer Center Clinical ( Site 6907)
COMPLETEDNew York, New York, 10032, United States
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FALP-UIDO ( Site 6400)
RECRUITINGSantiago, Region M. de Santiago, 7500921, Chile
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Facharztzentrum Eppendorf-Facharztzentrum Eppendorf ( Site 6807)
RECRUITINGHamburg, 20249, Germany
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Faculty of Medicine Siriraj Hospital ( Site 6102)
RECRUITINGBangkoknoi, Bangkok, 10700, Thailand
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Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 5200)
RECRUITINGMilan, Lombardy, 20133, Italy
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Fudan University Shanghai Cancer Center ( Site 5513)
RECRUITINGShanghai, Shanghai Municipality, 200032, China
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Hematology-Oncology Associates of Central NY, P.C. ( Site 6925)
RECRUITINGEast Syracuse, New York, 13057, United States
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Henan Cancer Hospital ( Site 5504)
RECRUITINGZhengzhou, Henan, 450008, China
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Hospital Nossa Senhora da Conceição ( Site 6301)
RECRUITINGPorto Alegre, Rio Grande do Sul, 91350-200, Brazil
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Hôpitaux Universitaires de Genève (HUG) ( Site 6701)
RECRUITINGGeneva, Canton of Geneva, 1211, Switzerland
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IBCC - Instituto Brasileiro de Controle do Câncer ( Site 6304)
RECRUITINGSão Paulo, 03102-006, Brazil
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ICESP - INSTITUTO DO CÂNCER DO ESTADO DE SÃO PAULO ( Site 6300)
RECRUITINGSão Paulo, 01246-000, Brazil
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IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori"-Oncologia Medica ( Site 5207)
RECRUITINGMeldola, Emilia-Romagna, 47014, Italy
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Kantonsspital Graubünden-Medizin ( Site 6700)
RECRUITINGChur, Kanton Graubünden, 7000, Switzerland
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Liga Norte Riograndense Contra o Câncer ( Site 6303)
RECRUITINGNatal, Rio Grande do Norte, 59062-000, Brazil
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NCT-Department of Medical Oncology ( Site 6809)
RECRUITINGHeidelberg, Baden-Wurttemberg, 69120, Germany
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National Cheng Kung University Hospital ( Site 6001)
RECRUITINGTainan, 704, Taiwan
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National Taiwan University Hospital-Oncology ( Site 6000)
RECRUITINGTaipei, 10048, Taiwan
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Norton Hospital-Norton Cancer Institute - Downtown ( Site 6900)
COMPLETEDLouisville, Kentucky, 40202, United States
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Oslo universitetssykehus, Radiumhospitalet ( Site 6501)
RECRUITINGOslo, 0379, Norway
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Ospedale San Raffaele-Oncologia Medica ( Site 5202)
RECRUITINGMilan, 20132, Italy
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Pitie Salpetriere University Hospital-Hepato-Gastro-Enterology ( Site 5102)
RECRUITINGParis, Île-de-France Region, 75013, France
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Ramathibodi Hospital ( Site 6103)
RECRUITINGRatchathewi, Bangkok, 10400, Thailand
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Samsung Medical Center-Division of Hematology/Oncology ( Site 5900)
RECRUITINGSeoul, 06351, South Korea
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Sir Run Run Shaw Hospital of Zhejiang University School of Medicine ( Site 5510)
RECRUITINGHangzhou, Zhejiang, 310016, China
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Songklanagarind hospital ( Site 6101)
RECRUITINGHat Yai, Changwat Songkhla, 90110, Thailand
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Taipei Veterans General Hospital ( Site 6005)
RECRUITINGTaipei, 112, Taiwan
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The 900th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army ( Site 5501)
RECRUITINGFuzhou, Fujian, 350025, China
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The Cancer and Hematology Centers ( Site 6912)
RECRUITINGGrand Rapids, Michigan, 49503, United States
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The First Affiliated Hospital of Nanchang University ( Site 5514)
RECRUITINGNanchang, Jiangxi, 330000, China
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The First Affiliated hospital of Xiamen University ( Site 5503)
RECRUITINGXiamen, Fujian, 361003, China
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UCLA Hematology/Oncology - Santa Monica ( Site 6905)
RECRUITINGLos Angeles, California, 90404, United States
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UPMC Hillman Cancer Center-UPMC ( Site 6904)
RECRUITINGPittsburgh, Pennsylvania, 15232, United States
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Universitaetsklinikum Carl Gustav Carus Dresden-Medical Dept I - Medical Oncology ( Site 6806)
RECRUITINGDresden, Saxony, 01307, Germany
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Universitaetsklinikum Duesseldorf-Gastroenterology, Hepatology and Infectiology ( Site 6802)
RECRUITINGDüsseldorf, North Rhine-Westphalia, 40225, Germany
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University of Arizona Cancer Center-University of Arizona Cancer Center ( Site 6927)
RECRUITINGTucson, Arizona, 85719, United States
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University of Texas MD Anderson Cancer Center ( Site 6920)
RECRUITINGHouston, Texas, 77030, United States
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Xinjiang Medical University Cancer Hospital - Urumqi ( Site 5506)
ACTIVE_NOT_RECRUITINGÜrümqi, Xinjiang, 841100, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can AI-Guided home training boost recovery from gastric cancer surgery?
- Can a new drug combo revive Immunotherapy's power against resistant tumors?
- A high-tech camera may take the guesswork out of spotting a dangerous surgery complication
- Can switching cancer therapy early extend life in stomach cancer?
- Blood test score may flag High-Risk esophageal surgery patients
- Can a new drug combo shrink Hard-to-Treat tumors?