New hope for stomach cancer: experimental drug combo trial opens

NCT ID NCT06469944

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study tests new experimental drugs combined with standard chemotherapy and immunotherapy for people with advanced stomach, gastroesophageal junction, or esophageal cancer that cannot be removed by surgery or has spread. About 160 participants will receive the combination to see if it is safe and helps shrink tumors. The goal is to find better treatment options for this hard-to-treat cancer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Asan Medical Center-Department of Oncology ( Site 5901)

    RECRUITING

    Seoul, 05505, South Korea

  • Azienda Ospedaliero Universitaria Pisana ( Site 5206)

    RECRUITING

    Pisa, Tuscany, 56126, Italy

  • Beijing Cancer hospital-Digestive Oncology ( Site 5500)

    RECRUITING

    Beijing, Beijing Municipality, 100142, China

  • Bradford Hill Norte ( Site 6407)

    RECRUITING

    Antofagasta, 1263521, Chile

  • Bradfordhill-Clinical Area ( Site 6401)

    RECRUITING

    Santiago, Region M. de Santiago, 8420383, Chile

  • CHU-BREST Cavale Blanche ( Site 5104)

    RECRUITING

    Brest, Finistere, 29200, France

  • CIC. ( Site 5100)

    RECRUITING

    Lille, Nord, 59037, France

  • Centro de Investigación del Maule ( Site 6408)

    RECRUITING

    Talca, Maule Region, 3481349, Chile

  • Centro de Oncología de Precisión-Oncology ( Site 6404)

    RECRUITING

    Santiago, Region M. de Santiago, 7560908, Chile

  • China Medical University Hospital ( Site 6007)

    RECRUITING

    Taichung, 404, Taiwan

  • Chulalongkorn Hospital ( Site 6104)

    RECRUITING

    Pathumwan, Bangkok, 10330, Thailand

  • Clínica Puerto Montt ( Site 6409)

    RECRUITING

    Port Montt, Los Lagos Region, 5500243, Chile

  • Clínica UC San Carlos de Apoquindo ( Site 6405)

    RECRUITING

    Santiago, Region M. de Santiago, 7620002, Chile

  • Columbia University Irving Medical Center-CUIMC Herbert Irving Comprehensive Cancer Center Clinical ( Site 6907)

    COMPLETED

    New York, New York, 10032, United States

  • FALP-UIDO ( Site 6400)

    RECRUITING

    Santiago, Region M. de Santiago, 7500921, Chile

  • Facharztzentrum Eppendorf-Facharztzentrum Eppendorf ( Site 6807)

    RECRUITING

    Hamburg, 20249, Germany

  • Faculty of Medicine Siriraj Hospital ( Site 6102)

    RECRUITING

    Bangkoknoi, Bangkok, 10700, Thailand

  • Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 5200)

    RECRUITING

    Milan, Lombardy, 20133, Italy

  • Fudan University Shanghai Cancer Center ( Site 5513)

    RECRUITING

    Shanghai, Shanghai Municipality, 200032, China

  • Hematology-Oncology Associates of Central NY, P.C. ( Site 6925)

    RECRUITING

    East Syracuse, New York, 13057, United States

  • Henan Cancer Hospital ( Site 5504)

    RECRUITING

    Zhengzhou, Henan, 450008, China

  • Hospital Nossa Senhora da Conceição ( Site 6301)

    RECRUITING

    Porto Alegre, Rio Grande do Sul, 91350-200, Brazil

  • Hôpitaux Universitaires de Genève (HUG) ( Site 6701)

    RECRUITING

    Geneva, Canton of Geneva, 1211, Switzerland

  • IBCC - Instituto Brasileiro de Controle do Câncer ( Site 6304)

    RECRUITING

    São Paulo, 03102-006, Brazil

  • ICESP - INSTITUTO DO CÂNCER DO ESTADO DE SÃO PAULO ( Site 6300)

    RECRUITING

    São Paulo, 01246-000, Brazil

  • IRCCS - Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori"-Oncologia Medica ( Site 5207)

    RECRUITING

    Meldola, Emilia-Romagna, 47014, Italy

  • Kantonsspital Graubünden-Medizin ( Site 6700)

    RECRUITING

    Chur, Kanton Graubünden, 7000, Switzerland

  • Liga Norte Riograndense Contra o Câncer ( Site 6303)

    RECRUITING

    Natal, Rio Grande do Norte, 59062-000, Brazil

  • NCT-Department of Medical Oncology ( Site 6809)

    RECRUITING

    Heidelberg, Baden-Wurttemberg, 69120, Germany

  • National Cheng Kung University Hospital ( Site 6001)

    RECRUITING

    Tainan, 704, Taiwan

  • National Taiwan University Hospital-Oncology ( Site 6000)

    RECRUITING

    Taipei, 10048, Taiwan

  • Norton Hospital-Norton Cancer Institute - Downtown ( Site 6900)

    COMPLETED

    Louisville, Kentucky, 40202, United States

  • Oslo universitetssykehus, Radiumhospitalet ( Site 6501)

    RECRUITING

    Oslo, 0379, Norway

  • Ospedale San Raffaele-Oncologia Medica ( Site 5202)

    RECRUITING

    Milan, 20132, Italy

  • Pitie Salpetriere University Hospital-Hepato-Gastro-Enterology ( Site 5102)

    RECRUITING

    Paris, Île-de-France Region, 75013, France

  • Ramathibodi Hospital ( Site 6103)

    RECRUITING

    Ratchathewi, Bangkok, 10400, Thailand

  • Samsung Medical Center-Division of Hematology/Oncology ( Site 5900)

    RECRUITING

    Seoul, 06351, South Korea

  • Sir Run Run Shaw Hospital of Zhejiang University School of Medicine ( Site 5510)

    RECRUITING

    Hangzhou, Zhejiang, 310016, China

  • Songklanagarind hospital ( Site 6101)

    RECRUITING

    Hat Yai, Changwat Songkhla, 90110, Thailand

  • Taipei Veterans General Hospital ( Site 6005)

    RECRUITING

    Taipei, 112, Taiwan

  • The 900th Hospital of the Joint Logistics Support Force of the Chinese People's Liberation Army ( Site 5501)

    RECRUITING

    Fuzhou, Fujian, 350025, China

  • The Cancer and Hematology Centers ( Site 6912)

    RECRUITING

    Grand Rapids, Michigan, 49503, United States

  • The First Affiliated Hospital of Nanchang University ( Site 5514)

    RECRUITING

    Nanchang, Jiangxi, 330000, China

  • The First Affiliated hospital of Xiamen University ( Site 5503)

    RECRUITING

    Xiamen, Fujian, 361003, China

  • UCLA Hematology/Oncology - Santa Monica ( Site 6905)

    RECRUITING

    Los Angeles, California, 90404, United States

  • UPMC Hillman Cancer Center-UPMC ( Site 6904)

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

  • Universitaetsklinikum Carl Gustav Carus Dresden-Medical Dept I - Medical Oncology ( Site 6806)

    RECRUITING

    Dresden, Saxony, 01307, Germany

  • Universitaetsklinikum Duesseldorf-Gastroenterology, Hepatology and Infectiology ( Site 6802)

    RECRUITING

    Düsseldorf, North Rhine-Westphalia, 40225, Germany

  • University of Arizona Cancer Center-University of Arizona Cancer Center ( Site 6927)

    RECRUITING

    Tucson, Arizona, 85719, United States

  • University of Texas MD Anderson Cancer Center ( Site 6920)

    RECRUITING

    Houston, Texas, 77030, United States

  • Xinjiang Medical University Cancer Hospital - Urumqi ( Site 5506)

    ACTIVE_NOT_RECRUITING

    Ürümqi, Xinjiang, 841100, China

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