New combo therapy aims to control hard-to-treat multiple myeloma

NCT ID NCT05372354

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 37 times

Summary

This study is for people with multiple myeloma that has returned or stopped responding to treatment. It tests a new drug, CC-92480, combined with other therapies to see if it is safe and works. About 260 adults will take part. The goal is to find the best dose and check how well the combination controls the cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Alberta Health Services AHS - Foothills Medical Centre FMC

    RECRUITING

    Calgary, Alberta, T2N 5G2, Canada

    Contact Phone: •••-•••-••••

  • Churchill Hospital

    RECRUITING

    Oxford, Oxfordshire, OX3 7LE, United Kingdom

    Contact Phone: •••-•••-••••

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-••••

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

    Contact Phone: •••-•••-••••

  • Hospital Universitario Marques de Valdecilla

    RECRUITING

    Santander, 39008, Spain

    Contact Phone: •••-•••-••••

  • ICO - Hospital Germans Trias i Pujol

    RECRUITING

    Barcelona, 08026, Spain

    Contact Phone: •••-•••-••••

  • John Theurer Cancer Center at Hackensack UMC

    RECRUITING

    Hackensack, New Jersey, 07601, United States

    Contact Phone: •••-•••-••••

  • Johns Hopkins Medicine - The Sidney Kimmel Comprehensive Cancer Center

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-••••

  • Local Institution - 0001

    WITHDRAWN

    Leicester, Leicestershire, LE1 5WW, United Kingdom

  • Local Institution - 0014

    WITHDRAWN

    Liverpool, Merseyside, L7 8YA, United Kingdom

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10021, United States

    Contact

  • NIHR UCLH Clinical Research Facility

    RECRUITING

    London, W1T 7HA, United Kingdom

    Contact Phone: •••-•••-••••

  • Oslo University Hospital

    RECRUITING

    Oslo, Outside US and Canada, 0450, Norway

    Contact Phone: •••-•••-••••

  • The Christie NHS Foundation Trust

    RECRUITING

    Manchester, Greater Manchester, M20 4BX, United Kingdom

    Contact Phone: •••-•••-••••

  • UAB Comprehensive Cancer Center

    RECRUITING

    Birmingham, Alabama, 35249, United States

    Contact Phone: •••-•••-••••

  • University Health Network UHN - Princess Margaret Hospital PMH

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

    Contact Phone: •••-•••-••••

  • University of Alberta - Cross Cancer Institute

    RECRUITING

    Edmonton, Alberta, T6G 1Z2, Canada

    Contact Phone: •••-•••-••••

Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.