New cocktail of four drugs shows promise against bone marrow cancer
NCT ID NCT04009109
First seen Jan 03, 2026 · Last updated May 14, 2026 · Updated 19 times
Summary
This study tests a combination of four drugs (lenalidomide, ixazomib, dexamethasone, and daratumumab) in people newly diagnosed with multiple myeloma who are not eligible for a stem cell transplant. The goal is to see if adding two extra drugs to standard maintenance therapy can keep the cancer from coming back longer. About 79 participants will receive the drugs for 12 cycles, then continue with either one or three drugs for up to two years.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Gibbs Cancer Center & Research Institute/Spartanburg Regional Healthcare
Spartanburg, South Carolina, 29303, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Northern Light Eastern Maine Medical Center
Bangor, Maine, 04401, United States
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SUNY Upstate Medical Center
Syracuse, New York, 13210, United States
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University of Nebraska Medical Center
Omaha, Nebraska, 68152, United States
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University of North Carolina
Chapel Hill, North Carolina, 27514, United States
Conditions
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