Breakthrough depression pill enters final testing phase

NCT ID NCT06058039

Recruiting now Disease control Sponsor: Neumora Therapeutics, Inc. Source: ClinicalTrials.gov ↗

Summary

This study is testing whether a new oral medication called NMRA-335140 can reduce symptoms of major depression. Over 6 weeks, 332 adults with moderate-to-severe depression will receive either the active drug or a placebo pill, with neither participants nor doctors knowing which is which. The main goal is to see if the medication significantly improves depression scores compared to placebo.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Neumora Investigator Site
COMPLETED

Cerritos, California, 90703, United States
Neumora Investigator Site
RECRUITING

Irvine, California, 92614, United States
Neumora Investigator Site
RECRUITING

Long Beach, California, 90807, United States
Neumora Investigator Site
RECRUITING

San Diego, California, 92103, United States
Neumora Investigator Site
RECRUITING

San Francisco, California, 94107, United States
Neumora Investigator Site
RECRUITING

New Haven, Connecticut, 06520, United States
Neumora Investigator Site
RECRUITING

Brandon, Florida, 33511, United States
Neumora Investigator Site
RECRUITING

Hialeah, Florida, 33012, United States
Neumora Investigator Site
RECRUITING

Hialeah, Florida, 33016, United States
Neumora Investigator Site
RECRUITING

Jacksonville, Florida, 32256, United States
Neumora Investigator Site
ACTIVE_NOT_RECRUITING

Miami, Florida, 33143, United States
Neumora Investigator Site
RECRUITING

Miami, Florida, 33165, United States
Neumora Investigator Site
RECRUITING

Miami Beach, Florida, 33140, United States
Neumora Investigator Site
COMPLETED

Palm Bay, Florida, 32905, United States
Neumora Investigator Site
RECRUITING

Pembroke Pines, Florida, 33024, United States
Neumora Investigator Site
ACTIVE_NOT_RECRUITING

Pompano Beach, Florida, 33060, United States
Neumora Investigator Site
ACTIVE_NOT_RECRUITING

Saint Augustine, Florida, 32086, United States
Neumora Investigator Site
RECRUITING

Atlanta, Georgia, 30328, United States
Neumora Investigator Site
RECRUITING

Decatur, Georgia, 30030, United States
Neumora Investigator Site
RECRUITING

Savannah, Georgia, 31405, United States
Neumora Investigator Site
RECRUITING

Springfield, Massachusetts, 01103, United States
Neumora Investigator Site
RECRUITING

St Louis, Missouri, 63141, United States
Neumora Investigator Site
COMPLETED

Omaha, Nebraska, 68112, United States
Neumora Investigator Site
RECRUITING

Berlin, New Jersey, 08009, United States
Neumora Investigator Site
RECRUITING

New York, New York, 10029, United States
Neumora Investigator Site
RECRUITING

New York, New York, 10036, United States
Neumora Investigator Site
ACTIVE_NOT_RECRUITING

Staten Island, New York, 10310, United States
Neumora Investigator Site
RECRUITING

Charlotte, North Carolina, 28211, United States
Neumora Investigator Site
RECRUITING

Austin, Texas, 78759, United States
Neumora Investigator Site
RECRUITING

DeSoto, Texas, 75115, United States
Neumora Investigator Site
RECRUITING

Fort Worth, Texas, 76104, United States
Neumora Investigator Site
ACTIVE_NOT_RECRUITING

Plano, Texas, 75093, United States
Neumora Investigator Site
COMPLETED

Cherven Bryag, Pleven, 5980, Bulgaria
Neumora Investigator Site
RECRUITING

Sofia, Sofia-Grad, 1408, Bulgaria
Neumora Investigator Site
RECRUITING

Sofia, Sofia-Grad, 1463, Bulgaria
Neumora Investigator Site
ACTIVE_NOT_RECRUITING

Sofia, Sofia-Grad, 1680, Bulgaria
Neumora Investigator Site
RECRUITING

Kardzhali, 6600, Bulgaria
Neumora Investigator Site
COMPLETED

Pleven, 5800, Bulgaria
Neumora Investigator Site
RECRUITING

Targovishte, 7700, Bulgaria
Neumora Investigator Site
RECRUITING

Varna, 9020, Bulgaria
Neumora Investigator Site
RECRUITING

Pilsen, Plzen, 301 00, Czechia
Neumora Investigator Site
ACTIVE_NOT_RECRUITING

Prague, Prague, 186 00, Czechia
Neumora Investigator Site
RECRUITING

Kladno, 272 01, Czechia
Neumora Investigator Site
COMPLETED

Prague, 109 00, Czechia
Neumora Investigator Site
RECRUITING

Helsinki, Etelä-Suomen Lääni, 00100, Finland
Neumora Investigator Site
COMPLETED

Turku, Etelä-Suomen Lääni, 20520, Finland
Neumora Investigator Site
ACTIVE_NOT_RECRUITING

Oulu, Oulun Lääni, 90100, Finland
Neumora Investigator Site
RECRUITING

Clermont-Ferrand, Auvergne-Rhône-Alpes, 63000, France
Neumora Investigator Site
RECRUITING

Douai, Hauts-de-France, 59500, France
Neumora Investigator Site
RECRUITING

Montpellier, Hérault, 34295, France
Neumora Investigator Site
ACTIVE_NOT_RECRUITING

Angers, Maine-et-Loire, 49100, France
Neumora Investigator Site
RECRUITING

La Roche-sur-Yon, Vendée, 85000, France
Neumora Investigator Site
ACTIVE_NOT_RECRUITING

Poitiers, Vienne, 86000, France
Neumora Investigator Site
RECRUITING

Berlin, 10117, Germany
Neumora Investigator Site
RECRUITING

Berlin, 10629, Germany
Neumora Investigator Site
RECRUITING

Berlin, 13187, Germany
Neumora Investigator Site
COMPLETED

Hamburg, 20253, Germany
Neumora Investigator Site
RECRUITING

Suchy Las, Greater Poland Voivodeship, 62-002, Poland
Neumora Investigator Site
RECRUITING

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-133, Poland
Neumora Investigator Site
RECRUITING

Wroclaw, Lower Silesian Voivodeship, 50-414, Poland
Neumora Investigator Site
COMPLETED

Lublin, Lublin Voivodeship, 20-109, Poland
Neumora Investigator Site
COMPLETED

Lublin, Lublin Voivodeship, 20-582, Poland
Neumora Investigator Site
RECRUITING

Bialystok, Podlaskie Voivodeship, 15-879, Poland
Neumora Investigator Site
COMPLETED

Gdansk, Pomeranian Voivodeship, 80-438, Poland
Neumora Investigator Site
RECRUITING

Lund, Skåne County, 222 22, Sweden
Neumora Investigator Site
ACTIVE_NOT_RECRUITING

Stockholm, Stockholm County, 113 29, Sweden
Neumora Investigator Site #1
COMPLETED

Varna, 9020, Bulgaria
Neumora Investigator Site #1
COMPLETED

Kladno, South Bohemian, 272 01, Czechia
Neumora Investigator Site #1
COMPLETED

Berlin, 10117, Germany
Neumora Investigator site
RECRUITING

Miami, Florida, 33174, United States
Neumora Investigator site
RECRUITING

Miami Springs, Florida, 33166, United States

Conditions

Explore the condition pages connected to this study.

MAJOR DEPRESSIVE DISORDER