New triple therapy aims to shrink head and neck tumors before surgery

NCT ID NCT07552558

First seen May 10, 2026 · Last updated May 13, 2026 · Updated 1 time

Summary

This study tests whether giving three treatments together before surgery can improve outcomes for people with advanced head and neck cancer. Participants will receive radiation, an immunotherapy drug (pembrolizumab), and an experimental drug (ficerafusp alfa) before standard surgery. The goal is to see if this combination is safe and can eliminate more cancer cells. About 45 adults with HPV-negative head and neck cancer will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

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    Contact Phone: •••-•••-•••• Email: •••••@•••••

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    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

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