New combo aims to outperform standard therapy in Tough-to-Treat colon cancer

NCT ID NCT07235293

First seen Nov 19, 2025 · Last updated May 15, 2026 · Updated 24 times

Summary

This study tests if a new combination of drugs (DSP107 and atezolizumab) works better than an existing treatment (fruquintinib) for people with advanced colorectal cancer that is microsatellite stable (MSS). About 90 adults who have already tried other therapies will be randomly assigned to one of the two treatments. Researchers will track how long participants live and monitor side effects to see if the new combo improves outcomes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alfred Hospital

    RECRUITING

    Melbourne, Victoria, 3004, Australia

    Contact

  • Austin Health

    RECRUITING

    Heidelberg, Victoria, 3084, Australia

    Contact

  • Chris O'brien Lifehouse

    RECRUITING

    Camperdown, New South Wales, 2050, Australia

    Contact

  • Duke University Medical Center - Duke Cancer Center

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact

  • Flinders Medical Centre SA

    RECRUITING

    Bedford Park, South Australia, 5042, Australia

    Contact

  • Footscray Hospital - Western Health

    RECRUITING

    Footscray, Victoria, 3011, Australia

    Contact

  • Icon Cancer Centre

    RECRUITING

    South Brisbane, Queensland, 4101, Australia

    Contact

  • Mayo Clinic

    NOT_YET_RECRUITING

    Florida City, Florida, 32224, United States

    Contact

  • Monash Health

    RECRUITING

    Clayton, Victoria, 3168, Australia

    Contact

  • Sir Charles Gairdner Hospital

    RECRUITING

    Nedlands, Western Australia, 6009, Australia

    Contact

  • Sunshine Hospital - Western Health

    RECRUITING

    Saint Albans, Victoria, 3021, Australia

    Contact

  • The Queen Elizabeth Hospital

    RECRUITING

    Woodville, Adelaide, 5011, Australia

    Contact

  • The University of Texas MD Anderson Cancer Center

    NOT_YET_RECRUITING

    Texas City, Texas, 77030, United States

    Contact

  • UPMC Hillman Cancer Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

    Contact

  • University of Colarodo Cancer Center

    NOT_YET_RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

  • Westmead Hospital

    RECRUITING

    Westmead, New South Wales, 2145, Australia

    Contact

Conditions

Explore the condition pages connected to this study.