New hope for Tough-to-Treat colon cancer? trial tests experimental combo

NCT ID NCT06948448

Recruiting now Disease control Sponsor: Ono Pharmaceutical Co. Ltd Source: ClinicalTrials.gov ↗

Summary

This study is testing whether adding two new immunotherapy drugs (ONO-4578 and Opdivo®) to standard chemotherapy works better than standard care alone for people with a specific type of advanced colorectal cancer. It will involve about 144 adults who have not yet received treatment for their advanced cancer and whose tumors test positive for a marker called PD-L1. The main goals are to see if the new combination shrinks tumors more effectively and is safe for patients.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Baylor Scott & White Medical Center
RECRUITING

Temple, Texas, 76508, United States
Blue Ridge Cancer Care
RECRUITING

Salem, Virginia, 24153, United States
CHU Besançon - Hôpital Jean Minjoz
RECRUITING

Besançon, Doubs, France
CHU Bordeaux - Hôpital Haut-Lévêque
RECRUITING

Pessac, Gironde, France
CHU Poitiers - Hôpital la Milétrie
RECRUITING

Poitiers, Vienne, France
Centre Leon Berard
RECRUITING

Lyon, Rhone, France
Chru De Nantes Hotel-Dieu
RECRUITING

Nantes, Loire Atlantique, France
Hospital General Universitario de Valencia
RECRUITING

Valencia, Valencia, Spain
Hospital Universitario 12 de Octubre
RECRUITING

Madrid, Madrid, Spain
Hospital Universitario Reina Sofia
RECRUITING

Córdoba, Córdoba, Spain
Hospital Universitario Virgen del Rocio
RECRUITING

Seville, Sevilla, Spain
Hôpital Européen Georges Pompidou
RECRUITING

Paris, Paris, France
Hôpital Saint-Antoine
RECRUITING

Paris, Paris, France
Hôpital de la Timone
RECRUITING

Marseille, Marseille, France
Istituto Clinico Humanitas
RECRUITING

Milan, Italy, Italy
Istituto Europeo di Oncologia
RECRUITING

Milan, Italy, Italy
Kobe City Medical Center General Hospital
RECRUITING

Hyōgo, Kobe-shi, Japan
Mayo Clinic Arizona
RECRUITING

Phoenix, Arizona, 85054, United States
Mayo Clinic Florida
RECRUITING

Jacksonville, Florida, 32224, United States
National Hospital Organization Osaka National Hospital
RECRUITING

Osaka, Osaka-shi, Japan
Osaka General Medical Center
RECRUITING

Osaka, Osaka-shi, Japan
Osaka International Cancer Institute
RECRUITING

Osaka, Osaka-shi, Japan
Princess Margaret Cancer Centre- University Health Network
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Rocky Mountain Cancer Centers, LLP
RECRUITING

Lone Tree, Colorado, 80124, United States
The Ohio State University Comprehensive Cancer Center
RECRUITING

Columbus, Ohio, 43221, United States
Thomas Jefferson University, Sidney Kimmel Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
USC Norris Comprehensive Cancer Center
RECRUITING

Los Angeles, California, 90033, United States
Virginia Oncology Associates
RECRUITING

Norfolk, Virginia, 23502, United States

Conditions

Explore the condition pages connected to this study.

COLORECTAL CANCER