New 'Ready-Made' cancer therapy trial seeks to tame tough blood cancers

NCT ID NCT03666000

Summary

This early-stage trial is testing the safety and early effectiveness of a new type of CAR T-cell therapy called azer-cel in adults whose B-cell blood cancers have returned or not responded to prior treatments. The therapy uses donor immune cells (allogeneic) engineered to target cancer, aiming to be an 'off-the-shelf' option. The study will first find a safe dose and then see how well the treatment works for conditions like non-Hodgkin lymphoma and B-cell acute lymphoblastic leukemia.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Banner MD Anderson Cancer Center

    COMPLETED

    Gilbert, Arizona, 85234, United States

  • Barbara Ann Karmanos Cancer Institute (Wayne State University)

    COMPLETED

    Detroit, Michigan, 48201, United States

  • Barwon Health - Andrew Love Cancer Centre

    RECRUITING

    Geelong, Victoria, 3320, Australia

    Contact

  • Baylor University Medical Center

    RECRUITING

    Dallas, Texas, 75246, United States

    Contact

    Contact

  • City of Hope

    COMPLETED

    Duarte, California, 91010, United States

  • Columbia University Irving Medical Center/New York Presbyterian Hospital

    RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact

  • Dana-Farber Cancer Institute

    COMPLETED

    Boston, Massachusetts, 02215, United States

  • Duke University

    COMPLETED

    Durham, North Carolina, 27708, United States

  • H. Lee Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

    Contact

  • Lifespan Cancer Institute at Rhode Island Hospital

    RECRUITING

    Providence, Rhode Island, 02903, United States

    Contact

    Contact

  • Liverpool Hospital

    RECRUITING

    Liverpool, New South Wales, 2170, Australia

    Contact

  • MD Anderson

    COMPLETED

    Houston, Texas, 77030, United States

  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

    Contact

    Contact

  • Northside Hospital Cancer Institute

    RECRUITING

    Atlanta, Georgia, 30342, United States

    Contact

    Contact

  • Ohio State University

    COMPLETED

    Columbus, Ohio, 43210, United States

  • Royal Adelaide Hospital

    RECRUITING

    Adelaide, South Australia, 5000, Australia

    Contact

  • Royal Prince Alfred Hospital

    RECRUITING

    Camperdown, New South Wales, 2050, Australia

    Contact

  • St Vincent's Hospital Melbourne

    RECRUITING

    Fitzroy, Victoria, 3065, Australia

    Contact

  • Tufts Medical Center

    RECRUITING

    Boston, Massachusetts, 02111, United States

    Contact

    Contact

  • University of Maryland

    RECRUITING

    Baltimore, Maryland, 21201, United States

    Contact

    Contact

  • University of Minnesota

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact

    Contact

  • Weill Cornell Medical College - NY Presbyterian Hospital

    COMPLETED

    New York, New York, 10021, United States

  • Winship Cancer Institute Emory University

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.