Scientists test 'Living Drug' from donors to fight tough leukemia

NCT ID NCT05507827

Summary

This early-stage trial is testing the safety of a new, two-part treatment for adults with B-cell acute lymphoblastic leukemia (ALL) that has come back or is hard to treat. The treatment involves a strong chemotherapy regimen, a special stem cell transplant (Orca-T), and an infusion of immune cells from a matched donor that are engineered to hunt and kill leukemia cells (CD19/CD22-CAR T cells). The main goal is to see if this combined approach can fight the cancer effectively without causing severe complications from the transplant.

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Contacts and locations

Locations

  • Stanford Cancer Center

    Palo Alto, California, 94305, United States

Conditions

Explore the condition pages connected to this study.