New weapon targets Cancer's immune shields

NCT ID NCT05537740

Summary

This early-stage study is testing a new immunotherapy drug called BAY 3375968 for people with advanced solid tumors that have not responded to standard treatments. The drug aims to boost the immune system's ability to fight cancer by targeting specific cells that suppress immunity. Researchers will test the drug alone and combined with an existing immunotherapy (pembrolizumab) to find safe doses and see if it shows early signs of effectiveness against several cancer types.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Antwerp University Hospital | Oncology Department

    Antwerp, 2650, Belgium

  • CHU de Liège

    Liège, 4000, Belgium

  • Centre Oscar Lambret - Service Oncologie

    Lille, 59000, France

  • Clinica Universidad de Navarra | Madrid | Oncologia

    Madrid, 28027, Spain

  • Clinica Universidad de Navarra | Pamplona | Oncologia

    Pamplona, Navarre, 31008, Spain

  • Ghent University Hospital | Drug Research Unit Department

    Ghent, 9000, Belgium

  • Guangdong Provincial People's Hospital

    Guangzhou, Guangdong, 510000, China

  • Hospital Universitari Vall D Hebron | Oncologia Medica

    Barcelona, 08035, Spain

  • Hospital Universitario Hm Sanchinarro | Oncologia Medica

    Madrid, 28050, Spain

  • Institut Bergonie - Unicancer Nouvelle Aquitaine - Service Oncologie medicale

    Bordeaux, 33000, France

  • Institut Gustave Roussy - Departement d'Innovation Therapeutique et d'Essais Precoces (DITEP)

    Villejuif, 94805, France

  • Institut de Cancerologie Ouest - Saint Herblain - Oncologie medicale

    Saint-Herblain, 44800, France

  • Jilin Cancer Hospital

    Changchun, Jilin, 130000, China

  • LinYi Cancer Hospital (Linyi Tumor Hospital)

    Linyi, 276001, China

  • National Cancer Center Singapore - Oncology Department

    Singapore, 168583, Singapore

  • National University Hospital Medical Centre

    Singapore, 119074, Singapore

  • OncoCare Cancer Centre | Gleneagles Medical Centre

    Singapore, 258499, Singapore

  • Princess Margaret Cancer Centre - Oncology Department

    Toronto, Ontario, M5G 2C4, Canada

  • Royal Marsden NHS Trust (Surrey)

    Sutton, Surrey, SM2 5PT, United Kingdom

  • START | San Antonio

    San Antonio, Texas, 78229, United States

  • South Texas Accelerated Research Therapeutics | START Rocky Mountain Region

    West Valley City, Utah, 84119, United States

  • The Christie NHS Foundation Trust - Christie Hospital

    Manchester, Greater Manchester, M204BX, United Kingdom

  • The Sixth Affiliated Hospital, Sun Yat-sen University

    Guangzhou, Guangdong, 510655, China

  • The University of Chicago Medical Center - Hyde Park - Hematology & Oncology

    Chicago, Illinois, 60637, United States

  • UNC Hospitals - UNC Lineberger Comprehensive Cancer Center

    Chapel Hill, North Carolina, 27514, United States

  • Universitair Ziekenhuis Leuven | Gasthuisberg Campus - General Medical Oncology

    Leuven, 3000, Belgium

Conditions

Explore the condition pages connected to this study.