New hope for tough cancers: first human test of targeted drug begins
NCT ID NCT03993873
Summary
This is an early-stage study to test a new oral drug called TPX-0022 (elzovantinib) in adults with advanced or spreading cancers that have specific changes in a gene called MET. The main goals are to find a safe dose, see how the body processes the drug, and get a first look at whether it can shrink or control tumors. The study will include people with certain types of lung cancer, stomach cancer, or other solid tumors that have these MET alterations.
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Contacts and locations
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Locations
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Local Institution - 2101
Houston, Texas, 77030-4009, United States
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Local Institution - 2102
La Jolla, California, 92093, United States
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Local Institution - 2103
St Louis, Missouri, 63110, United States
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Local Institution - 2104
Toledo, Ohio, 43614, United States
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Local Institution - 2105
Denver, Colorado, 80218, United States
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Local Institution - 2106
Ann Arbor, Michigan, 48109, United States
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Local Institution - 2107
Boston, Massachusetts, 02114, United States
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Local Institution - 2108
Orange, California, 92868, United States
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Local Institution - 2109
Boston, Massachusetts, 02215, United States
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Local Institution - 2111
Chicago, Illinois, 60637, United States
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Local Institution - 2112
Fairfax, Virginia, 22031, United States
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Local Institution - 2113
Detroit, Michigan, 48202, United States
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Local Institution - 4101
Madrid, 28050, Spain
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Local Institution - 4102
Pamplona, 31008, Spain
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Local Institution - 4103
Madrid, 28040, Spain
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Local Institution - 4104
Madrid, 28036, Spain
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Local Institution - 4201
Lyon, 69008, France
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Local Institution - 4202
La Tronche, Auvergne-Rhône-Alpes, 38700, France
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Local Institution - 4203
Saint-Mandé, Val-de-Marne, 94160, France
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Local Institution - 4204
Villejuif, Val-de-Marne, 94805, France
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Local Institution - 6301
Seoul, Seoul-teukbyeolsi [Seoul], 06351, South Korea
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Local Institution - 6302
Seoul, 120-752, South Korea
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Local Institution - 6303
Seoul, 03080, South Korea
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Local Institution - 6304
Seoul, 05505, North Korea
Conditions
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