Two-Pronged attack: experimental drug aims to Re-Engage immune system against tough cancers

NCT ID NCT04931654

Summary

This early-stage study is testing a new drug called AZD7789 in people with advanced lung or stomach cancers that have spread and stopped responding to standard immunotherapy. The main goals are to find a safe dose and see if the drug shows any signs of shrinking tumors. The drug is designed to block two different 'off-switches' on immune cells at once, hoping to help the body's own defenses fight the cancer more effectively.

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Contacts and locations

Locations

  • Research Site

    Atlanta, Georgia, 30322, United States

  • Research Site

    Fort Wayne, Indiana, 46804, United States

  • Research Site

    New York, New York, 10029, United States

  • Research Site

    Nashville, Tennessee, 37203, United States

  • Research Site

    Toronto, Ontario, M5G 2M9, Canada

  • Research Site

    Beijing, 100142, China

  • Research Site

    Guangzhou, 510060, China

  • Research Site

    Bordeaux, 33076, France

  • Research Site

    Rennes, 35000, France

  • Research Site

    Villejuif, 94805, France

  • Research Site

    Tbilisi, 0112, Georgia

  • Research Site

    Chūōku, 104-0045, Japan

  • Research Site

    Kashiwa, 277-8577, Japan

  • Research Site

    Chisinau, MD-2025, Moldova

  • Research Site

    Amsterdam, 1066 CX, Netherlands

  • Research Site

    Barcelona, 08035, Spain

  • Research Site

    Madrid, 28027, Spain

  • Research Site

    Ankara, 06010, Turkey (Türkiye)

  • Research Site

    Ankara, 06200, Turkey (Türkiye)

  • Research Site

    Ankara, 06800, Turkey (Türkiye)

  • Research Site

    Cordaleo, 35575, Turkey (Türkiye)

Conditions

Explore the condition pages connected to this study.