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New 'Smart Bomb' drug enters human testing for Tough-to-Treat cancers

NCT ID NCT07046923

Recruiting now Disease control Sponsor: Eli Lilly and Company Source: ClinicalTrials.gov ↗

Summary

This is the first human trial of a new experimental cancer drug called LY4175408. It is designed to target and deliver a toxic payload specifically to cancer cells that have a certain marker (PTK7). The study will test the drug's safety, side effects, and early signs of effectiveness in up to 240 people with advanced lung, breast, or endometrial cancers who have run out of standard treatment options.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Institute Hospital of JFCR

    RECRUITING

    Tokyo, 135-8550, Japan

  • Centre Leon Berard

    RECRUITING

    Lyon, 69373, France

  • Columbia University

    RECRUITING

    New York, New York, 10032, United States

  • Community Health Network

    NOT_YET_RECRUITING

    Indianapolis, Indiana, 46250, United States

  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

  • Florida Cancer Specialists - Lake Nona - Sarah Cannon Research Institute

    RECRUITING

    Orlando, Florida, 32827, United States

  • Florida Cancer Specialists - Sarasota

    RECRUITING

    Sarasota, Florida, 34236, United States

  • Hospital Universitario 12 de Octubre

    RECRUITING

    Madrid, 28041, Spain

  • Hospital Universitario Vall d'Hebron

    RECRUITING

    Barcelona, 08035, Spain

  • Institut Gustave Roussy

    RECRUITING

    Villejuif, 94805, France

  • John Theurer Cancer Center At Hackensack UMC

    RECRUITING

    Hackensack, New Jersey, 07601, United States

  • Kyoto University Hospital

    RECRUITING

    Kyoto, 606-8507, Japan

  • MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

  • NEXT Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

  • National Cancer Center Hospital

    RECRUITING

    Tokyo, 104-0045, Japan

  • START Mountain Region

    RECRUITING

    West Valley City, Utah, 84119, United States

  • Samsung Medical Center

    RECRUITING

    Seoul, 06351, South Korea

  • Sarah Cannon Research Institute

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Severance Hospital, Yonsei University Health System

    RECRUITING

    Seoul, 03722, South Korea

  • Stanford Cancer Center

    RECRUITING

    Stanford, California, 94305, United States

  • The Ohio State University (OSU) Wexner Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

  • The University of Chicago Medical Center (UCMC)

    RECRUITING

    Chicago, Illinois, 60637, United States

  • Washington University

    RECRUITING

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.

CARCINOMA, NON-SMALL-CELL LUNG ENDOMETRIAL NEOPLASMS NEOPLASM METASTASIS SMALL CELL LUNG CARCINOMA TRIPLE NEGATIVE BREAST CANCER