First human trial launches for new pill that activates immune system to fight cancer

NCT ID NCT05614102

Summary

This early-stage study is testing a new oral immunotherapy drug called BAY2965501 in people with advanced solid tumors that have spread and are hard to treat. Researchers want to find the safest dose and see how the body handles the drug, both alone and combined with other cancer treatments. The drug works by activating the body's own T-cells, a type of immune cell, to attack the cancer.

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Contacts and locations

Locations

  • Antwerp University Hospital | Oncology Department

    Antwerp, 2650, Belgium

  • Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center

    Shenzhen, 518172, China

  • Cancer Hospital, Chinese Academy of Medical Sciences

    Beijing, 100000, China

  • Clinica Universidad De Navarra | Oncologia

    Madrid, 28027, Spain

  • Freeman Hospital

    Newcastle upon Tyne, Tyne and Wear, NE7 7DN, United Kingdom

  • Ghent University Hospital | Drug Research Unit Department

    Ghent, 9000, Belgium

  • Guy's and St Thomas' NHS Foundation Trust - Guy's Hospital

    London, Greater London, SE1 9RT, United Kingdom

  • Hospital Hm Nou Delfos | Oncologia

    Barcelona, 08023, Spain

  • Hospital Universitari Vall D Hebron | Oncologia

    Barcelona, 08035, Spain

  • Hospital Universitario Hm Sanchinarro | Oncologia

    Madrid, 28050, Spain

  • National Cancer Center Hospital East

    Kashiwa, Chiba, 277-8577, Japan

  • Oxford University Hospitals NHS Foundation Trust | Churchill Hospital - Oncology

    Oxford, Oxfordshire, OX3 7LE, United Kingdom

  • Royal Marsden NHS Trust (Surrey)

    Sutton, Surrey, SM2 5PT, United Kingdom

  • START | San Antonio

    San Antonio, Texas, 78229, United States

  • Samsung Medical Center - Oncology Department

    Seoul, 135-710, South Korea

  • Sarah Cannon Research Institute at HCA HealthONE Presbyterian St. Luke's

    Denver, Colorado, 80218, United States

  • Seoul National University Bundang Hospital

    Seongnam-si, Gyeonggido, 13620, South Korea

  • Severance Hospital, Yonsei University Health System - Oncology Department

    Seoul, Seoul Teugbyeolsi, 03722, South Korea

  • Sir Run Run Shaw Hospital, Zhejiang Univ. School of Medicine - Oncology Department

    Hangzhou, Zhejiang, 310016, China

  • UPMC Hillman Cancer Center

    Pittsburgh, Pennsylvania, 15232, United States

Conditions

Explore the condition pages connected to this study.