Early cancer drug trial halted after testing in 92 patients

NCT ID NCT03446040

Summary

This early-stage study aimed to find a safe dose for a new experimental drug called BMS-986258, testing it alone and combined with an existing immunotherapy (nivolumab) in people with advanced cancers. It enrolled 92 participants with specific advanced tumors who had already tried standard treatments. The main goal was to check for side effects and determine how much of the drug the body could tolerate, but the trial was terminated before completion.

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Contacts and locations

Locations

  • Local Institution - 0002

    Germantown, Tennessee, 38138, United States

  • Local Institution - 0004

    Los Angeles, California, 90033, United States

  • Local Institution - 0005

    Pittsburgh, Pennsylvania, 15232, United States

  • Local Institution - 0006

    Los Angeles, California, 90033, United States

  • Local Institution - 0007

    Aurora, Colorado, 80045, United States

  • Local Institution - 0008

    Chuo-ku, Tokyo, 1040045, Japan

  • Local Institution - 0009

    Kobe, Hyōgo, 6500017, Japan

  • Local Institution - 0010

    Grand Rapids, Michigan, 49546, United States

  • Local Institution - 0012

    Lebanon, New Hampshire, 03756, United States

  • Local Institution - 0013

    Westmead, New South Wales, 2145, Australia

  • Local Institution - 0014

    Edmonton, Alberta, T6X 1E8, Canada

  • Local Institution - 0015

    Melbourne, Victoria, 3084, Australia

  • Local Institution - 0016

    Cincinnati, Ohio, 45267, United States

  • Local Institution - 0018

    Ann Arbor, Michigan, 48109-5912, United States

  • Local Institution - 0019

    Vancouver, British Columbia, V5Z 4E6, Canada

  • University Of Iowa Hospitals And Clinics

    Iowa City, Iowa, 52242, United States

Conditions

Explore the condition pages connected to this study.